Browsing Medicine Research by Author "D'Souza, Martin J."
Now showing items 1-5 of 5
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An Adjuvanted Inactivated SARS-CoV-2 Microparticulate Vaccine Delivered Using Microneedles Induces a Robust Immune Response in Vaccinated Mice
Vijayanand, Sharon; Patil, Smital; Menon, Ipshita; Braz Gomes, Keegan; Kale, Akanksha; Bagwe, Priyal; Uddin, Mohammad N.; Zughaier, Susu M.; D’Souza, Martin J.... more authors ... less authors ( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)SARS-CoV-2, the causal agent of COVID-19, is a contagious respiratory virus that frequently mutates, giving rise to variant strains and leading to reduced vaccine efficacy against the variants. Frequent vaccination against ... -
Assessment of In Vitro Immunostimulatory Activity of an Adjuvanted Whole-Cell Inactivated Neisseria gonorrhoeae Microparticle Vaccine Formulation
Bagwe, Priyal; Bajaj, Lotika; Gala, Rikhav P.; D’souza, Martin J.; Zughaier, Susu M. ( MDPI , 2022 , Article)The emergence of drug-resistant gonorrhea infections worldwide combined with the lack of a vaccine is alarming. We prepared a novel microparticulate (MP) vaccine formulation using whole-cell inactivated Neisseria gonorrhoeae ... -
Meningococcal Vaccines: Challenges and Prospects.
Bagwe, Priyal; Bajaj, Lotika; Gala, Rikhav; Zughaier, Susu M; Uddin, Mohammad N; D'Souza, Martin J... more authors ... less authors ( MDPI , 2020 , Article)is a gram-negative bacterium that causes a severe acute infection, called the meningococcal disease [...]. -
Microneedles: A new generation vaccine delivery system
Menon, Ipshita; Bagwe, Priyal; Gomes, Keegan Braz; Bajaj, Lotika; Gala, Rikhav; Uddin, Mohammad N.; D’souza, Martin J.; Zughaier, Susu M.... more authors ... less authors ( MDPI , 2021 , Article Review)Transdermal vaccination route using biodegradable microneedles is a rapidly progressing field of research and applications. The fear of painful needles is one of the primary reasons most people avoid getting vaccinated. ... -
Oral Vaccine Delivery: The Coming Age of Particulate Vaccines to Elicit Mucosal Immunity
Gala, Rikhav P.; Bajaj, Lotika; Bansal, Amit; Gomes, Keegan Braz; Joshi, Devyani; Menon, Ipshita; Zaman, Rokon Uz; Zughaier, Susu M.; D’Souza, Marissa; Popescu, Carmen; D’Souza, Nigel; Knipp, Gregory T.; D’Souza, Martin J.... more authors ... less authors ( Springer , 2020 , Book chapter)With the evolution of different challenging diseases, there is an urgent need of vaccine development against them to save millions of lives around the world. Particlulate delivery system plays an important role by acting ...