Browsing Medicine Research by Author "Rachid, Ousama"
Now showing items 1-4 of 4
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A systematic review of stability of medicines used in emergency medical service settings
Rachid, Ousama; Obasi, Joy; Mohamed Ibrahim, MohamedIzham; Diab, Mohammad; Al-Moslih, Ayad; Makhlouf, Ahmed; Alinier, Guillaume... more authors ... less authors ( Hamad bin Khalifa University Press (HBKU Press) , 2020 , Article)Background: Temperature, among several environment conditions like humidity, is known to impact medicine stability 1,2 . In emergency medical service (EMS) settings, it is often challenging to control these conditions. In ... -
Emerging innate biological properties of nano-drug delivery systems: A focus on PAMAM dendrimers and their clinical potential
Kheraldine, Hadeel; Rachid, Ousama; M Habib, Abdella; Al Moustafa, Ala-Eddin; F. Benter, Ibrahim ( Elsevier , 2021 , Article)Drug delivery systems or vectors are usually needed to improve the bioavailability and effectiveness of a drug through improving its pharmacokinetics/pharmacodynamics at an organ, tissue or cellular level. However, emerging ... -
Intravenous fluids in hot pre-hospital environments: Thermal and physical stability of normal saline after exposure to simulated stress conditions
Rachid, Ousama; Akkbik, Mohammed; Makhlouf, Ahmed; Moslih, Ayad; Al Shaikh, Loua; Alinier, Guillaume... more authors ... less authors ( Hamad bin Khalifa University Press (HBKU Press) , 2022 , Article)Background: Normal saline 0.9 % (NS) is the most widespread crystalloid used as a life-saving intravenous (IV) fluid. 1 NS contains sodium and chloride in equal concentrations and is subject to thermal stress conditions ... -
Substantial cell apoptosis provoked by naked PAMAM dendrimers in HER2-positive human breast cancer via JNK and ERK1/ERK2 signalling pathways
Hadeel, Kheraldine; Gupta, Ishita; Alhussain, Hashim; Jabeen, Aayesha; Cyprian, Farhan S.; Akhtar, Saghir; Al Moustafa, Ala-Eddin; Rachid, Ousama... more authors ... less authors ( Elsevier , 2021 , Article)HER2-positive breast cancer is one of its most challenging subtypes, forming around 15–25% of the total cases. It is characterized by aggressive behavior and treatment resistance. On the other hand, poly (amidoamine) (PAMAM) ...