Medicine Research: Recent submissions
Now showing items 281-300 of 1934
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Design, Synthesis, and Anti-Inflammatory Evaluation In Vitro and In Silico of Novel Flavone Derivatives
( John Wiley and Sons Inc , 2025 , Article)A series of flavone derivatives (4–6) were synthesized via cyclization of 2′ hydroxychalcones 3 into flavonols 4 using the Algar–Flynn–Oyamada reaction. Flavonols 4 were then O-cyanomethylated to flavones 5, followed by ... -
Preliminary Findings on the Use of Array Comparative Genomic Hybridization in Youth with Autism Spectrum Disorder in Qatar: A Case Series Study
( Routledge , 2025 , Article)Autism Spectrum Disorder (ASD) is a neurodevelopmental condition with rising prevalence. Traditional diagnostic approaches often lack biological markers, making precision in diagnosis challenging. This study explores the ... -
A methodology to estimate the benefits and costs of stakeholder engagement in a transport decision-making process
( Emerald Publishing , 2025 , Article)Purpose – The objective of this paper is to propose a methodology to estimate the benefits and costs of stakeholder engagement (SE). Indeed, in the transport sector, it is consolidated that a good decision-making process ... -
Deep learning and vision transformers-based framework for breast cancer and subtype identification
( Springer Science and Business Media Deutschland GmbH , 2025 , Article)Breast cancer, marked by uncontrolled cell growth in breast tissue, is the most common cancer among women and a second-leading cause of cancer-related deaths. Among its types, ductal and lobular carcinomas are the most ... -
Effectiveness of human albumin for clinical outcome in aneurysmal subarachnoid hemorrhages: a protocol for randomized controlled (HASH) trial
( BioMed Central Ltd , 2025 , Article)Background: Aneurysmal subarachnoid hemorrhage (aSAH) is a dreadful acute neurological condition with an overwhelmingly high rate of associated morbidities and mortality. Despite leaping advancement in neurosurgical ... -
Risk Factors of Difficult Intubation in Patients with Severe Obesity Undergoing Bariatric Surgery: A Retrospective Cohort Study
( Springer , 2025 , Article)Background: Obesity poses significant challenges by altering upper airway anatomy and making mask ventilation and tracheal intubation difficult. In 2023, 46.1% women and 35.9% men > 18 years were classified as obese in ... -
Comparison of complications in isolated aesthetic liposuction procedures across different techniques: a systematic review and meta-analysis
( Springer Science and Business Media Deutschland GmbH , 2025 , Article)Background: Liposuction has emerged as one of the most common cosmetic procedures globally, increasing by more than two-fold since 1997. While different liposuction techniques exist, each with distinct advantages and ... -
The prevalence of depression and anxiety symptoms and their associated factors among patients with cancer in Qatar: A cross-sectional study
( HBKU Press , 2025 , Article)Background: Cancer is a significant global health challenge. One of the biggest health issues that cancer patients face is depression and anxiety. This has a significant impact on their quality of life and treatment outcomes. ... -
The influence of circadian rhythm disruption during Ramadan on metabolic responses to physical activity: a pilot study
( Frontiers Media SA , 2025 , Article)Background: Circadian rhythms and sleep patterns are important regulators of metabolic health. During Ramadan intermittent fasting (RIF), the sleep–wake cycles are often disrupted, which can affect physical activity (PA) ... -
DeepRaman: Implementing surface-enhanced Raman scattering together with cutting-edge machine learning for the differentiation and classification of bacterial endotoxins
( Elsevier , 2025 , Article)To classify raw SERS Raman spectra from biological materials, we propose DeepRaman, a new architecture inspired by the Progressive Fourier Transform and integrated with the scalogram transformation approach. Unlike standard ... -
Surgical repair techniques in hypospadias with unfavorable urethral plate: A systematic review and network meta-analysis
( Elsevier , 2025 , Article Review)IntroductionHypospadias is one of the most common urogenital malformations in male newborns. Numerous techniques exist for repairing hypospadias, including urethral advancement, tubularized incised plate (TIP), flaps, and ... -
Response to the Letter to the editors on “International consensus on research priorities in hypospadias using a Delphi study approach”
( Elsevier , 2025 , Article)Thank you for your thoughtful comments on the article “International consensus on research priorities in hypospadias using a Delphi study approach.” [1] We appreciate the opportunity to address some of the points you ... -
A bibliometric analysis of the top cited articles on anterior cruciate ligament reconstruction with anterolateral ligament reconstruction
( Elsevier , 2024 , Article)BackgroundIn recent years, there has been a marked increase in research interest in anterior cruciate ligament (ACL) reconstruction combined with anterolateral ligament (ALL) augmentation. PurposeThis study aims to provide ... -
Self-reported outcomes in adults with hypospadias: A meta-analysis of patient satisfaction and quality-of-life metrics
( Elsevier , 2025 , Article)IntroductionHypospadias reconstruction seeks to correct structural problems associated with this congenital condition to improve patient quality-of-life (QoL) and overall well-being. While corrective surgery can lead to ... -
Evaluating the utility of ChatGPT in enhancing parental education and clinical support in hypospadias care
( Elsevier , 2025 , Article)IntroductionHypospadias is a prevalent congenital anomaly that requires effective parental education. Current online resources often exceed recommended readability levels, potentially hindering understanding. This study ... -
From bone sentinel to immune savant: Vitamin D and its receptor’s pharmacology
( Elsevier , 2025 , Other)The journey of vitamin D from a simple bone health nutrient to a complex immunomodulator is a testament to the evolving and dynamic nature of scientific understanding. Reflecting on the centennial of vitamin D’s discovery, ... -
Pharmacotherapeutic opportunities within the Hippo signaling pathway
( Elsevier , 2025 , Other)The Hippo pathway is a master of cellular regulation. It modulates intricate mechanisms that govern organ size, tissue homeostasis, and regeneration. Guo et al (2025) dissect the pathway’s multifaceted nature. Their article ... -
Drugging dancing protein clouds: A close look at disorder-based drug design
( Elsevier , 2025 , Other)Since it was established in the late 19th century, the traditional “lock-and-key” model of protein functionality has been foundational in biochemistry, particularly with respect to protein structure and function (Fischer, ... -
Pharmacological strategies to bridge the gap between cancer and cardiovascular therapeutics
( Elsevier , 2025 , Article)Throughout the history of biomedical research, few endeavors have proven as formidable as the quest to defeat or overcome cancer and cardiovascular diseases (CVDs). Indeed, these twin scourges continue to distress humanity ... -
Beyond the stomach stall: Current and emerging pharmacotherapeutics for gastroparesis
( Elsevier , 2025 , Article)Gastroparesis is a gastrointestinal motility disorder characterized by delayed gastric emptying, which precipitates symptoms like nausea, vomiting, early satiety, and bloating. Diagnosis requires evidence of delayed gastric ...
