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AuthorQassim, Suelen H
AuthorChemaitelly, Hiam
AuthorAyoub, Houssein H
AuthorAlMukdad, Sawsan
AuthorTang, Patrick
AuthorHasan, Mohammad R
AuthorYassine, Hadi M
AuthorAl-Khatib, Hebah A
AuthorSmatti, Maria K
AuthorAbdul-Rahim, Hanan F
AuthorNasrallah, Gheyath K
AuthorAl-Kuwari, Mohamed Ghaith
AuthorAl-Khal, Abdullatif
AuthorCoyle, Peter
AuthorKaleeckal, Anvar Hassan
AuthorShaik, Riyazuddin Mohammad
AuthorLatif, Ali Nizar
AuthorAl-Kuwari, Einas
AuthorJeremijenko, Andrew
AuthorButt, Adeel A
AuthorBertollini, Roberto
AuthorAl-Romaihi, Hamad Eid
AuthorAl-Thani, Mohamed H
AuthorAbu-Raddad, Laith J
Available date2022-06-12T04:57:12Z
Publication Date2022-05-27
Publication NameJournal of Travel Medicine (JTM)
Identifierhttp://dx.doi.org/10.1093/jtm/taac068
CitationSuelen H Qassim, MBBS MPH, Hiam Chemaitelly, PhD, Houssein H Ayoub, PhD, Sawsan AlMukdad, MSc, Patrick Tang, MD PhD, Mohammad R Hasan, PhD, Hadi M Yassine, PhD, Hebah A Al-Khatib, PhD, Maria K Smatti, MSc, Hanan F Abdul-Rahim, PhD, Gheyath K Nasrallah, PhD, Mohamed Ghaith Al-Kuwari, MD, Abdullatif Al-Khal, MD, Peter Coyle, MD, Anvar Hassan Kaleeckal, MSc, Riyazuddin Mohammad Shaik, MSc, Ali Nizar Latif, MD, Einas Al-Kuwari, MD, Andrew Jeremijenko, MD, Adeel A Butt, MBBS MS, Roberto Bertollini, MD MPH, Hamad Eid Al-Romaihi, MD, Mohamed H Al-Thani, MD, Laith J Abu-Raddad, PhD, Effects of BA.1/BA.2 subvariant, vaccination, and prior infection on infectiousness of SARS-CoV-2 omicron infections, Journal of Travel Medicine, 2022;, taac068, https://doi.org/10.1093/jtm/taac068
ISSN1708-8305
URIhttp://hdl.handle.net/10576/32061
AbstractCompared to BA.1, BA.2 was associated with lower RT-qPCR cycle threshold (Ct) value-3.53 fewer cycles (95% CI: 3.46-3.60), signifying higher infectiousness. This may reflect higher viral load and/or longer duration of infection for BA.2. Natural immunity from previous infection and booster vaccination were associated with less infectious breakthrough infections.
SponsorThe authors are grateful for support from the Biomedical Research Program and the Biostatistics, Epidemiology, and Biomathematics Research Core, both at Weill Cornell Medicine-Qatar, as well as for support provided by the Ministry of Public Health, Hamad Medical Corporation, and Sidra Medicine. The authors are also grateful for the Qatar Genome Programme and Qatar University Biomedical Research Center for institutional support for the reagents needed for the viral genome sequencing. Statements made herein are solely the responsibility of the authors. The funders of the study had no role in study design, data collection, data analysis, data interpretation, or writing of the Article
Languageen
PublisherOxford University Press
SubjectCOVID-19
Omicron
breakthrough infection
cohort study
epidemiology
immunity
sub-lineage
subvariant
vaccine
TitleEffects of BA.1/BA.2 subvariant, vaccination, and prior infection on infectiousness of SARS-CoV-2 omicron infections.
TypeArticle
dc.accessType Open Access


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