Pharmacy Research: Recent submissions
Now showing items 181-200 of 1293
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Medication use problems and factors affecting older adults in primary healthcare
( Elsevier , 2023 , Article)Background: As the largest demographic group utilizing primary healthcare facilities, older adults often face the challenge of managing multiple chronic illnesses, leading to numerous medications. Objective: The present ... -
Synthesis of curcuma longa doped cellulose grafted hydrogel for catalysis, bactericidial and insilico molecular docking analysis
( Elsevier , 2023 , Article)Curcumin (diferuloylmethane), the primary curcuminoid in turmeric rhizome, has been acknowledged as a bioactive compound for numerous pharmacological activities. Nonetheless, the hydrophobic nature, rapid metabolism, and ... -
Correction to: A qualitative assessment of medical students' readiness for virtual clerkships at a Qatari university during the COVID-19 pandemic (BMC Medical Education, (2023), 23, 1, (186), 10.1186/s12909-023-04117-3)
( BioMed Central Ltd , 2023 , Other)Correction: BMC Medical Education (2023) 23:186 Following publication of the original article [1], due to a typesetting error, references [19] and [20] were written incorrectly. The correct references are given below: [19] ... -
Eutectics in Pharmacy Curriculum: A Simple Demonstration with Pharmaceutical Relevance
( ACS Publications , 2023 , Article)In chemistry, a eutectic mixture refers to a mixture of two or more components at which the lowest possible freezing point is observed. This phenomenon is covered in a wide range of curricula such as physics, chemistry, ... -
Epigenetic inhibitors and their role in cancer therapy
( Elsevier , 2023 , Article)Epigenetic modifications to DNA are crucial for normal cellular and biological functioning. DNA methylation, histone modifications, and chromatin remodeling are the most common epigenetic mechanisms. These changes are ... -
Endothelin Receptor Blocker Reverses Breast Cancer–Induced Cardiac Remodeling
( Elsevier , 2023 , Article)Background: Although some cancer therapies have overt and/or subclinical cardiotoxic effects that increase subsequent cardiovascular risk in breast cancer patients, we have recently shown that the breast tumor itself can ... -
Comprehensive evaluation of the pharmacological and toxicological effects of γ-valerolactone as compared to γ-hydroxybutyric acid: Insights from in vivo and in silico models
( Elsevier , 2023 , Article)Γ-valerolactone (GVL), marketed online as “Tranquilli-G” and “excellent Valium”, is used as a legal substitute for γ-hydroxybutyric acid (GHB); however, until now, GVL has only been connected to one Drug-Facilitated Sexual ... -
Can we use normal saline stored under stress conditions? A simulated prehospital emergency medical setting
( Elsevier Ltd , 2023 , Article)Background: Data on stability and suitability to use normal saline stored under stress conditions in ambulances is lacking. Objective: We aimed to study the impact of exposure to extreme temperature variations on normal ... -
Deciphering the complexities of cancer cell immune evasion: Mechanisms and therapeutic implications
( Elsevier , 2023 , Article Review)Cancer immune evasion is one of the principal mechanisms leading to the progression and metastatization of the disease. Despite the migration and infiltration at the tumor site of immune cells, multiple factors can influence ... -
A Prospective Cohort Study (OUTSTRIP-COVID) on Functional and Spirometry Outcomes in COVID-19 ICU Survivors at 3 Months
( Taylor & Francis Group , 2023 , Article)Purpose: COVID-19 pandemic resulted in a significant number of critical care admissions secondary to severe pneumonia and acute respiratory distress syndrome. We evaluated the short-, medium-and long-term outcomes of lung ... -
Protein tyrosine phosphatase 1B inhibition improves endoplasmic reticulum stress-impaired endothelial cell angiogenic response: A critical role for cell survival
( Spandidos publications , 2021 , Article)Endoplasmic reticulum (ER) stress contributes to endothelial dysfunction, which is the initial step in atherogenesis. Blockade of protein tyrosine phosphatase (PTP)1B, a negative regulator of insulin receptors that is ... -
Serum immune mediators as novel predictors of response to anti-PD-1/PD-L1 therapy in non-small cell lung cancer patients with high tissue-PD-L1 expression
( Frontiers Media S.A. , 2023 , Article)Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related morbidity and mortality worldwide. Immune checkpoint inhibitors (ICIs) including anti-PD-1 and anti-PD-L1 antibodies, have significantly changed the ... -
Mental Health Prescribers' Perceptions on the Use of Pharmacogenetic Testing in the Management of Depression in the Middle East and North Africa Region
( Dove Medical Press Ltd , 2023 , Article)Objective: A wide variety of commercial pharmacogenetic (PGx) tools are available worldwide to guide treatment selection for depression based on individuals’ genetic profiles. However, the use of genetic testing to inform ... -
Sleep Quality and Sleep Hygiene Behaviours Among University Students in Qatar
( Dove Medical Press Ltd , 2023 , Article)Background: Insomnia is a highly prevalent health problem, affecting about one-third of the adult population globally. University students are at a high risk for developing insomnia due to the stressful nature of academic ... -
Pill-burden and its association with treatment burden among patients with advanced stages of chronic kidney disease
( Elsevier , 2023 , Article)Introduction: Chronic kidney disease (CKD) is associated with multimorbidity and high treatment burden. Pill-burden is one component of the overall treatment burden. However, little is known about its magnitude and ... -
Inappropriate polypharmacy management versus deprescribing: A review on their relationship
( John Wiley and Sons Inc , 2023 , Article Review)Medication burden and polypharmacy are highly prevalent among patients with multimorbidity. There have been multiple initiatives to overcome polypharmacy and medication burden in patients with multimorbidity. These initiatives ... -
Impact of Clinical Pharmacist Interventions on Economic Outcomes in a Cardiology Setting in Qatar
( Elsevier , 2023 , Article)We sought to investigate the economic impact of preventing adverse events in a cardiology setting in Qatar as an effect of the clinical pharmacist as an intervention. This is a retrospective study of interventions by ... -
Economic impact of clinical pharmacist interventions in a general tertiary hospital in Qatar
( Public Library of Science , 2023 , Article)Background With an increasingly strained health system budgets, healthcare services need to continually demonstrate evidence of economic benefits. This study sought to evaluate the economic impact of interventions initiated ... -
Percutaneous Mitral-Valve Intervention for Secondary Mitral Regurgitation: Data From Real-Life
( Elsevier , 2023 , Article Review)Many questions were raised due to the divergent results between cardiovascular outcomes assessment of the MitraClip percutaneous therapy for heart failure patients with functional mitral regurgitation (COAPT) and multicenter ... -
Nanotargeted Delivery of Immune Therapeutics in Type 1 Diabetes
( John Wiley and Sons Inc , 2023 , Article)Immune therapeutics holds great promise in the treatment of type 1 diabetes (T1D). Nonetheless, their progress is hampered by limited efficacy, equipoise, or issues of safety. To address this, a novel and specific nanodelivery ...
