Pharmacy Research: Recent submissions
Now showing items 221-240 of 1293
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Quality by Design Approach in Liposomal Formulations: Robust Product Development
( Multidisciplinary Digital Publishing Institute (MDPI) , 2022 , Article)Nanomedicine is an emerging field with continuous growth and differentiation. Liposomal formulations are a major platform in nanomedicine, with more than fifteen FDA-approved liposomal products in the market. However, as ... -
Obesity Paradox among Heart Failure with Reduced Ejection Fraction Patients: A Retrospective Cohort Study
( Multidisciplinary Digital Publishing Institute (MDPI) , 2022 , Article)Background and Objectives: There is consensus on the negative effects of obesity on the development of heart failure. However, several studies have suggested that obesity may have paradoxical survival benefits in heart ... -
Evaluation of disaster medicine preparedness among healthcare profession students: A cross-sectional study in pakistan
( Multidisciplinary Digital Publishing Institute (MDPI) , 2020 , Article)Background: Disasters are devastating incidents, especially when occurring suddenly and causing damage, great loss of life, or suffering. Disasters can affect health and the social and economic development of a nation. The ... -
Aryl Hydrocarbon Receptor Promotes Cell Growth, Stemness Like Characteristics, and Metastasis in Human Ovarian Cancer via Activation of PI3K/Akt, β-Catenin, and Epithelial to Mesenchymal Transition Pathways
( Multidisciplinary Digital Publishing Institute (MDPI) , 2022 , Article)Ovarian cancer (OC) ranks first in cancer-related deaths out of all female reproductive malignancies with high-pitched tumor relapse and chemoresistance. Several reports correlate cancer occurrences with exposure to ... -
Visfatin: A Possible Role in Cardiovasculo-Metabolic Disorders
( Multidisciplinary Digital Publishing Institute (MDPI) , 2020 , Article)Visfatin/NAMPT (nicotinamide phosphoribosyltransferase) is an adipocytokine with several intriguing properties. It was first identified as pre-B-cell colony-enhancing factor but turned out to possess enzymatic functions ... -
Preventive and Therapeutic Effects of Punica granatum (Pomegranate) in Respiratory and Digestive Diseases: A Review
( Multidisciplinary Digital Publishing Institute (MDPI) , 2022 , Article)The pomegranate fruit is made of white to deep purple seeds that are enclosed in a white, spongy, astringent membrane, also known as pericarp, covered by a thick red skin and a crown-shaped calyx. It contains a variety of ... -
Formulation of boron encapsulated smart nanocapsules for targeted drug delivery to the brain
( Multidisciplinary Digital Publishing Institute (MDPI) , 2021 , Article)Drug delivery through the Blood–Brain Barrier (BBB) represents a significant challenge. Despite the current strategies to circumvent the BBB, nanotechnology offers unprecedented opportunities for combining selective delivery, ... -
Review of Progress and Prospects in Research on Enzymatic and Non- Enzymatic Biofuel Cells; Specific Emphasis on 2D Nanomaterials
( Bentham Science Publishers , 2022 , Article)Energy generation from renewable sources and effective management are two critical challenges for sustainable development. Biofuel Cells (BFCs) provide an elegant solution by combining these two tasks. BFCs are defined by ... -
The Role of p90 Ribosomal S6 Kinase (RSK) in Tyrosine Kinase Inhibitor (TKI)-Induced Cardiotoxicity
( Springer , 2023 , Article Review)Targeted therapy, such as tyrosine kinase inhibitors (TKIs), has been approved to manage various cancer types. However, TKI-induced cardiotoxicity is a limiting factor for their use. This issue has raised the need for ... -
Role of methylglyoxal in diabetic cardiovascular and kidney diseases: Insights from basic science for application into clinical practice
( Bentham Science Publishers , 2018 , Article Review)Background: The incidence and prevalence of diabetes mellitus are increasing globally at alarming rates. Cardiovascular and renal complications are the major cause of morbidity and mortality in patients with diabetes. ... -
Effect of pharmacogenetic-based decision support tools in improving depression outcomes: A systematic review
( Taylor & Francis Group , 2021 , Article Review)Objective: Evidence supporting the utility of pharmacogenetic (PGX) tests in depression is scarce. The main objectives of this study were to summarize, update, and assess the quality of the available evidence regarding PGX ... -
Evaluation of the effect of hypericum triquetrifolium turra on memory impairment induced by chronic psychosocial stress in rats: Role of BDNF
( Taylor & Francis Group , 2020 , Article)Background: Chronic psychosocial stress impairs memory function and leads to a depression-like phenotype induced by a persistent status of oxidative stress. Hypericum perforatum L. (St. John’s wort) is widely used to relieve ... -
Evaluation of the Validity of SAMe-TT2R2 Score in a Cohort of Venous Thromboembolism Patients Treated With Warfarin
( SAGE Publications Inc. , 2020 , Article)Low SAMe-TT2R2 score of <2 was validated as a predictor of optimum anticoagulation control, reflected by mean time in therapeutic range (TTR) above 65% to 70%, among warfarin-treated atrial fibrillation patients. This study ... -
Assessing Pharmacists Knowledge and Attitude Toward the Direct Oral Anticoagulants in Qatar
( SAGE Publications Inc. , 2020 , Article)Pharmacists were found to play a key role in anticoagulation care. In order to make an appropriate selection and counselling regarding direct oral anticoagulants (DOACs), pharmacists should be knowledgeable and abiding by ... -
Effect of mobile text messages on antiretroviral medication adherence and patient retention in early HIV care: An open-label, randomized, single center study in south Florida
( BioMed Central Ltd. , 2020 , Article)Background People with HIV (PHIV) with limited access to health services often experience suboptimal antiretroviral therapy (ART) adherence. We investigated whether a daily text messaging intervention improves ART adherence ... -
A Comparative Approach to Screen the Capability of Raman and Infrared (Mid- and Near-) Spectroscopy for Quantification of Low-Active Pharmaceutical Ingredient Content Solid Dosage Forms: The Case of Alprazolam
( SAGE Publications Inc. , 2020 , Article)Content uniformity is a critical attribute for potent and low-dosage formulations of active pharmaceutical ingredient (API) that, in addition to the formulation parameters, plays pivotal role during pharmaceutical development ... -
Acceptance and attitudes toward COVID-19 vaccines: A cross-sectional study from Jordan
( Public Library of Science , 2021 , Article)Vaccines are effective interventions that can reduce the high burden of diseases globally. However, public vaccine hesitancy is a pressing problem for public health authorities. With the availability of COVID-19 vaccines, ... -
Environmental Factors, Lifestyle Risk Factors, and Host Characteristics Associated With Philadelphia Negative Myeloproliferative Neoplasm: A Systematic Review
( SAGE Publications Ltd , 2021 , Article Review)Myeloproliferative neoplasms (MPNs) are clonal hematopoietic stem cell disorders characterized by the overproduction of mature myeloid cells and are often associated with an acquired genetic mutation of Janus Kinase2V617F. ... -
Efficacy and cost effectiveness of intravenous ferric carboxymaltose versus iron sucrose in adult patients with iron deficiency anaemia
( Public Library of Science , 2021 , Article)Background Iron deficiency anaemia (IDA) is a major health issues and common type of nutritional deficiency worldwide. For IDA treatment, intravenous (IV) iron is a useful therapy. Objective To determine the efficacy and ... -
The Dilemma of Peri-Procedural Warfarin Management: A Narrative Review
( SAGE Publications Inc. , 2021 , Article Review)Periprocedural vitamin K antagonist management is a complex process and inherently entails multiple clinical issues. Marked variations have been reported in different aspects of this process. These differences were noted ...
