Student Thesis & Dissertations: Recent submissions
Now showing items 861-880 of 1710
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THE ROLE OF ENTEROENDOCRINE SECRETED GUT PEPTIDE HORMONES IN MODULATING IMMUNITY AND METABOLISM IN DROSOPHILA MELANOGASTER
(2021 , Master Thesis)The intestine of all living organisms fosters an ecosystem of commensal microbiota that plays key roles in the maintenance of host health and pathology. Captivatingly, the influence of dysbiosis on the host has demonstrated ... -
THE IMPACT OF HSA-MIR-146A-5P ON HUMAN RETINAL ENDOTHELIAL CELLS IN DIABETIC CONDITIONS
(2021 , Master Thesis)Background: Diabetic retinopathy (DR) is a microvascular complication of diabetes that leads to visual impairment in the adult population with effective available therapy. Micro-Ribonucleic acids (miRNAs) are small (?22 ... -
GENERATION AND CHARACTERIZATION OF "OFF-THE-SHELF" CHIMERIC ANTIGEN RECEPTOR ENGINEERED T CELLS (CAR-T) TO TARGET CANCER PATIENTS WITH HEMATOLOGICAL MALIGNANCIES
(2021 , Master Thesis)Background: The usage of T cells engineered with a tumor-specific chimeric antigen receptor (CAR) for the therapeutic treatment of some types of hematological malignancies demonstrated great clinical success. However, the ... -
THE ROLE OF NUTRITIONAL STATUS AS AN EPIGENETIC MODULATOR IN TYPE 1 DIABETES IN PEDIATRIC POPULATION OF QATAR
(2021 , Master Thesis)Type 1 Diabetes Mellites (T1DM), is an autoimmune disorder caused by the destruction of pancreatic b?-cells and is considered to be among the most prevalent chronic conditions in Qatar. This study aimed to identify the ... -
DEVELOPMENT AND IN VIVO TESTING OF SMART NANOPARTICLES FOR ENHANCED ANTI-CANCER ACTIVITY AND REDUCED CARDIOTOXICITY ASSOCIATED WITH TYROSINE KINASE INHIBITORS
(2021 , Master Thesis)Tyrosine kinase inhibitors (TKIs) are new generation of anti-cancer drugs with very high efficiency against cancer cells. However, TKIs are associated with severe cardiotoxicity limiting their clinical benefits. One ... -
Cost-effectiveness Analysis of Ibuprofen versus Indomethacin or Paracetamol for the Treatment of Patent Ductus Arteriosus in Preterm Neonates
(2021 , Master Thesis)Objective: This thesis sought to evaluate the cost-effectiveness of oral paracetamol and intravenous (IV) indomethacin as alternatives to ibuprofen for patent ductus arteriosus (PDA) in neonates in Hamad Medical Corporation ... -
CLINICAL AND PHARMACOECONOMIC ANALYSES OF CDK4/6 INHIBITORS USE IN STAGE IV BREAST CANCER FEMALES IN THE STATE OF QATAR: A COMPARATIVE RETROSPECTIVE OBSERVATIONAL STUDY WITH COST-EFFECTIVENESS AND COST-UTILITY ANALYSES
(2021 , Master Thesis)Introduction: Cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitors are indicated in the first-line treatment of hormonal receptor positive and HER-2 negative (HR+/HER2- negative) advanced breast cancer. Although phase III ... -
MOLECULAR FEATURES OF TRIPLE NEGATIVE BREAST CANCER STEM CELLS: A GENE EXPRESSION PROFILING ANALYSIS OF MDA-MB-231 CELLS
(2021 , Master Thesis)Triple negative breast cancer (TNBC) is a chemoresistant subtype of female breast tumors. Chemoresistance is attributed to the presence of long-lived cancer stem cells (CSCs) responsible for therapy failure. This study ... -
MODULATION OF THE MOLECULAR EXPRESSION AND FUNCTION OF BCL-2 FAMILY PROTEINS BY THE ARYL HYDROCARBON RECEPTOR IN BREAST CANCER STEM CELLS OF THE MDA-MB-231
(2021 , Master Thesis)Breast cancer (BC) is a frequently occurring neoplasm in women and is a second major cause of cancer related deaths. Despite the remarkable advancements in the understanding of BC and its treatments, the diseases still ... -
COMMUNITY PHARMACISTS' SELF-PERCEIVED COMPETENCY, AND ENABLERS, AND BARRIERS TOWARDS THE MANAGEMENT OF COMMON MINOR AILMENTS IN QATAR
(2021 , Master Thesis)The study aimed to assess community pharmacists' self-perceived competency, and enablers and barriers towards managing common minor ailments in Qatar, and its predictors. A cross-sectional study, with pretested questionnaires, ... -
NASAL EXPRESSION OF ANIOTENSIN-CONVERTING ENZYME 2 (ACE2) IN CHILDREN AND ADULTS WITH COVID-19
(2021 , Master Thesis)"Emerging evidence suggests that the lower expression of SARS-CoV-2 entry factor angiotensin-converting enzyme 2 (ACE2) and transmembrane serine protease 2 (TMPRSS2) in the nasal epithelium of children may contribute to ... -
EVALUATION OF LABORATORY CLINICAL TRAINING INTERNSHIP OF A NAACLS ACCREDITED PROGRAM IN QATAR: GRADUATES PERSPECTIVE
(2021 , Master Thesis)Background: The medical laboratory educational programs (Medical Laboratory Science and Medical Laboratory Technology) accredited by the National Accrediting Agency for Clinical Laboratory Sciences (NAACLS) provide the ... -
COVID-19 VACCINATION KNOWLEDGE AND HESITANCY AMONG STUDENTS AND EMPLOYEES AT QATAR UNIVERSITY; A CROSS-SECTIONAL STUDY
(2021 , Professional Masters Project)Introduction: Vaccines are the most important and cost-effective public health tools known to control and prevent many infectious diseases. However, concerns regarding the safety and the need for a vaccine and reluctance ... -
BIOMEDICAL WASTE MANAGEMENT AWARENESS AMONG HEALTH SCIENCE STUDENTS AT QATAR UNIVERSITY
(2021 , Professional Masters Project)Introduction: Biomedical waste is any kind of waste that contains infectious or potentially infectious products that are generated during diagnosis, treatment, or research. At Qatar University (QU), the production of waste ... -
A COST-EFFECTIVENESS ANALYSIS FOR HIGH VERSUS LOW DOSE CAFFEINE FOR THE TREATMENT OF APNEA IN NEONATAL INTENSIVE CARE UNIT
(2021 , Master Thesis)Objective: This thesis sought to evaluate the cost effectiveness of high dose (HD) caffeine as alternative therapy over the standard low dose (LD) caffeine for apnea of prematurity (AOP) in neonates, in Hamad Medical ... -
ASSESSMENT OF ADHERENCE, BARRIERS AND STRENGTHS TO ADHERENCE AMONG ADOLESCENTS WITH TYPE 1 DIABETES IN QATAR: PERSPECTIVES OF PATIENTS AND THEIR CAREGIVERS
(2021 , Master Thesis)Background: Metabolic control among adolescents with type 1 diabetes mellitus (T1DM) is generally poor. Non-adherence is one of the contributors to this poor glycemic control, leading to high complication rates. The objective ... -
مدى امتلاك معلمات مرحلة الطفولة المبكرة بدولة قطر لمهارات إكساب الأطفال مهارات الوعي الصوتي
(2021 , Master Thesis)لقد هدفت الدراسة إلى تحديد مدى امتلاك معلمات مرحلة الطفولة المبكرة بدولة قطر لمهارات إكساب الأطفال مهارات الوعي الصوتي، ولتحقيق أهداف الدراسة؛ استخدمت الباحثة المنهج الكمي، وتكونت عينة الدراسة من ( 211 ) معلمة لغة عربية ... -
مدى تضمين مفاهيم التنمية المستدامة في كتب الدراسات الاجتماعية بدولة قطر
(2021 , Master Thesis)هدفت هذه الدراسة إلى معرفة مدى تضمين مفاهيم التنمية المستدامة في كتب الدراسات الاجتماعية بدولة قطر، وذلك باستخدام أسلوب تحليل المحتوى في جمع البيانات. تكون مجتمع الدراسة من كتب الدراسات الاجتماعية المقررة على طلبة الصفوف ... -
مدى توافر قيم التسامح والتعايش مع الآخر في محتوى كتب الدراسات الاجتماعية بالمرحلة الاعدادية في دولة قطر
(2021 , Master Thesis)هدفت الدراسة إلى الكشف عن مدى توافر قيم التسامح والتعايش مع الآخر في محتوى كتب الدراسات الاجتماعية بالمرحلة الاعدادية في دولة قطر؛ حيث سعت إلى الإجابة عن خمسة تساؤلات، تمحورت حول: تحديد قيم التسامح والتعايش مع الآخر ... -
The Prevalence of Statin Prescription for Primary Prevention of Arteriosclerotic Cardiovascular Disease Among Patients with Type 2 Diabetes in Qatar
(2021 , Master Thesis)Background: Qatar has one of the highest prevalence rates for diabetes in the world. Arteriosclerotic cardiovascular diseases (ASCVDs) are responsible for nearly 50% of deaths among patients with diabetes in Qatar. Treating ...
