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AuthorSharma, Bhavna
AuthorMehta, Aashna
AuthorFarooqui, Habib H
AuthorNegandhi, Himanshu
AuthorSelvaraj, Sakthivel
Available date2022-08-25T05:37:09Z
Publication Date2022-06-01
Publication NameCureus
Identifierhttp://dx.doi.org/10.7759/cureus.26367
CitationSharma B, Mehta A, Farooqui H H, et al. (June 27, 2022) Impact of the Drug Prices Control Order (2013) on the Utilization of Anticancer Medicines in India: An Interrupted Time-Series Analysis. Cureus 14(6): e26367. DOI 10.7759/cureus.26367
URIhttp://hdl.handle.net/10576/33425
AbstractObjectives The National Pharmaceutical Pricing Authority introduced a series of Drug Prices Control Orders since 1970 to regulate the prices of essential medicines in India. This study evaluated the impact of the Drug Prices Control Order of 2013 on the utilization of anticancer medicines in the Indian private sector. Methods We used monthly sales audit data for a period of 2012-15, provided by Intercontinental Medical Statistics (IMS) Health. Through interrupted time series design and segmented regression models, we estimated the change in utilization of anticancer medicines following the drug pricing policy implementation. Results Of 1556 anticancer drug packs, 22.3% (n= 347) were price-controlled. The policy led to an immediate monthly reduction of 27.3% (95% CI -38.6%, -13.9%; p=0.001) and a long-term monthly reduction of 0.7% (95% CI -1.6%, 0.3%; p=0.16) in price-controlled formulation's utilization. In the final study month, the price-controlled formulation's utilization was 5.03 thousand standard units lower than what would have been expected without the policy. Melphalan showed the highest immediate reduction, and alpha-interferon showed the highest long-term reduction in utilization. Conclusion Drug prices control order 2013 caused an immediate and long-term decline in the utilization of anticancer medicines in the Indian private sector. However, study data was limited to a specific part of the Indian anticancer drug market, which must be considered when interpreting findings.
Languageen
PublisherBMC
Subjectanticancer
dpco
drug prices control order
drug pricing policy
interrupted time series
TitleImpact of the Drug Prices Control Order (2013) on the Utilization of Anticancer Medicines in India: An Interrupted Time-Series Analysis.
TypeArticle
Issue Number6
Volume Number14
ESSN2168-8184
dc.accessType Open Access


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