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AuthorJohar, Al-Reem A.
AuthorAbu-Rub, Lubna I.
AuthorAl Mana, Hassan
AuthorYassine, Hadi M.
AuthorEltai, Nahla O.
Available date2022-09-25T09:28:50Z
Publication Date2022-09-12
Publication NameAnimal Production Science
Identifierhttp://dx.doi.org/10.1071/AN22233
CitationJohar Al-Reem A., Abu-Rub Lubna I., Al Mana Hassan, Yassine Hadi M., Eltai Nahla O. (2022) Microbiome engineering to combat antimicrobial resistance and upsurge productivity of food animals: a systematic review. Animal Production Science , https://doi.org/10.1071/AN22233
ISSN1836-0939
URIhttp://hdl.handle.net/10576/34433
AbstractExtensive antimicrobial usage in animal farming plays a prominent role in the antimicrobial resistance (AMR) crisis and is repeatedly highlighted as an area needing development under the ‘One Health’ approach. Alternative therapies such as microbiome products can be used as prophylaxis to help avoid infectious disease. However, a limited number of studies have focused on AMR-targeted microbiome products. We conducted this systematic review by using PRISMA guidelines to screen for literature that have evaluated food animals’ health when administrated with microbiome products targeting antimicrobial resistance (AMR) or antibiotic-resistant genes (ARGs). We searched and examined studies from SCOPUS, Web of Science, Embase, and Science direct databases for studies published up to November 2021, restricted to the English language. The findings of this review showed that microbiome products have a promising capability to tackle specific AMR/ARGs coupled with animal’s health and productivity improvement. Furthermore, our study showed that probiotics were the most favorable tested microbiome products, with the most targeted resistance being to tetracycline, macrolides, and beta-lactams. While microbiome products are promising alternatives to antibiotic prophylactics, there is a dearth of studies investigating their efficacy in targeting AMR. Thus, it is highly recommended to further investigate, develop, and improve the microbiome, to better understand its utility and circumvent its limitations.
SponsorThe authors thank Barzan holdings for the financial support.
Languageen
PublisherCSIRO Publishing
SubjectAMR
antimicrobials
ARG
bacteria
food animals
microbiome
microbiome products
probiotics
TitleMicrobiome engineering to combat antimicrobial resistance and upsurge productivity of food animals: a systematic review
TypeArticle
ESSN1836-5787
dc.accessType Open Access


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