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AuthorZvizdic, Zlatan
AuthorBecirovic, Naida
AuthorMilisic, Emir
AuthorJonuzi, Asmir
AuthorTerzic, Sabina
AuthorVranic, Semir
Available date2022-12-20T08:52:54Z
Publication Date2022-12-02
Publication NameMedicine (United States)
Identifierhttp://dx.doi.org/10.1097/MD.0000000000032148
CitationZvizdic, Zlatan MD, PhDa; Becirovic, Naida MDb; Milisic, Emir MD, PhDa; Jonuzi, Asmir MD, PhDa; Terzic, Sabina MD, PhDc; Vranic, Semir MD, PhDd,*. Epidemiologic and clinical characteristics of selected congenital anomalies at the largest Bosnian pediatric surgery tertiary center. Medicine 101(48):p e32148, December 02, 2022. | DOI: 10.1097/MD.0000000000032148
ISSN00257974
URIhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85143563322&origin=inward
URIhttp://hdl.handle.net/10576/37420
AbstractCongenital anomalies (CA) are any abnormality present at birth, either structural or functional, that may potentially affect an infant's health, development, and/or survival. There is a paucity of studies on clinical characteristics and outcomes of CA in Bosnia and Herzegovina, mainly due to the lack of a nationwide congenital malformations monitoring system. A 5-year hospital-based study was conducted to determine the prevalence at birth and clinical characteristics of selected major CA in Sarajevo Canton, Bosnia and Herzegovina. Ninety-one CA were observed from 2012 to 2016 (the overall prevalence was 39.6 cases/10,000 live births). The mean age of neonates at diagnosis was 3 days. The gastrointestinal tract was the most commonly affected system (76.9%), with esophageal atresia (EA) being the most frequent (17.6% of all CA). Major CA were more prevalent among preterm infants than term infants (P=.001), particularly in males (61.5% vs. 38.5%; P=.028; M:F ratio was 1.59). Multiple CA were seen in 37.4% of neonates. The overall mortality rate of neonates was 11%, and the median length of hospital stay was 19.8 days. Our study revealed the distribution and clinical patterns of common major CA in the largest tertiary care facility in Bosnia and Herzegovina. It also confirmed a relatively high mortality rate, which requires further efforts to improve the quality of neonatal care in the country.
Languageen
PublisherLippincott, Williams & Wilkins
Subjectclinical characteristics
major congenital anomalies
outcome
prevalence
surgery
TitleEpidemiologic and clinical characteristics of selected congenital anomalies at the largest Bosnian pediatric surgery tertiary center
TypeArticle
Issue Number48
Volume Number101
ESSN1536-5964
dc.accessType Open Access


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