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AuthorMarei, Hany E.
AuthorAlthani, Asmaa
AuthorAfifi, Nahla
AuthorHasan, Anwarul
AuthorCaceci, Thomas
AuthorCifola, Ingrid
AuthorCaratelli, Sara
AuthorSconocchia, Giuseppe
AuthorD’Agnano, Igea
AuthorCenciarelli, Carlo
Available date2023-03-29T08:06:11Z
Publication Date2022-12-01
Publication NameDiscover Oncology
Identifierhttp://dx.doi.org/10.1007/s12672-022-00514-0
CitationMarei, H.E., Althani, A., Afifi, N. et al. Glioma extracellular vesicles for precision medicine: prognostic and theragnostic application. Discov Onc 13, 49 (2022). https://doi.org/10.1007/s12672-022-00514-0
URIhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85132117188&origin=inward
URIhttp://hdl.handle.net/10576/41412
AbstractEV produced by tumour cells carry a diverse population of proteins, lipids, DNA, and RNA molecules throughout the body and appear to play an important role in the overall development of the disease state, according to growing data. Gliomas account for a sizable fraction of all primary brain tumours and the vast majority of brain malignancies. Glioblastoma multiforme (GBM) is a kind of grade IV glioma that has a very dismal prognosis despite advancements in diagnostic methods and therapeutic options. The authors discuss advances in understanding the function of extracellular vesicles (EVs), in overall glioma growth, as well as how recent research is uncovering the utility of EVs in glioma diagnostics, prognostic and therapeutics approaches.
Languageen
PublisherSpringer
SubjectDiagnosis
Extracellular vesicles
GBM
GSCs
Prognosis
Therapy
TitleGlioma extracellular vesicles for precision medicine: prognostic and theragnostic application
TypeArticle Review
Issue Number1
Volume Number13
dc.accessType Open Access


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