College of Medicine: المرسلات الحديثة

السجلات المعروضة 121 -- 140 من 1891

    • Indoleacetylglutamine Pathway Is a Potential Biomarker for Cardiovascular Diseases 

      Naja, Khaled; Anwardeen, Najeha; Al-Shafai, Mashael; Elrayess, Mohamed A. ( Multidisciplinary Digital Publishing Institute (MDPI) , 2025 , Article)
      Cardiovascular diseases (CVDs) remain a leading cause of global morbidity and mortality. Metabolomics allows for the identification of important biomarkers for CVDs, essential for early detection and risk assessment. This ...

    • Selective Activation of G Protein-coupled Estrogen Receptor 1 Attenuates Atherosclerosis 

      Haider, Mohammad Zulqurnain; Sahebkar, Amirhossein; Eid, Ali H. ( Bentham Science Publishers , 2024 , Article)
      Atherosclerosis remains a leading contributor to cardiovascular disease-associated morbidity and mortality. Interestingly, atherosclerosis-associated mortality rate is higher in men than women. This suggested a protective ...

    • Neratinib and metformin: A novel therapeutic approach against HER2-Positive Breast Cancer 

      Kheraldine, Hadeel; Hassan, Arij Fouzat; Saeed, Sumayyah; Merhi, Maysaloun; Mateo, Jericha Miles; ... more authors ( Elsevier , 2025 , Article)
      BackgroundHER2-positive breast cancer (BC) is highly aggressive with a poor prognosis. It is driven by HER2 oncoprotein activation/crosstalk with other receptors like EGFR/(HER1), HER3, and HER4, in addition to IGF-1R, ...

    • Readdressing the role of ADRA2A in Raynaud’s phenomenon: Methodological concerns and implications 

      Ali H., Eid ( Elsevier , 2025 , Other)
      We read, with excitement, the important and timely paper titled ‘‘Genetic and functional analysis of Raynaud’s syndrome implicates loci in vasculature and immunity’’ that appeared in volume 4, issue 9 of Cell Genomics in ...

    • Silicone Quaterium-22 Surfactant as an Eco-Friendly Carbon Steel Anticorrosive: Assessment of Corrosion Inhibition Properties and Ecotoxicity in Zebrafish Embryos 

      Shaito, Abdullah A.; Younes, Nadin; daas, sahar; Dosari, AL-Dana; Nasrallah, Dana F.; ... more authors ( Elsevier , 2025 , Article)
      Corrosion of carbon steel pipelines in the oil and gas industry presents operational and environmental challenges, requiring safer alternatives to toxic corrosion inhibitors. This study evaluates Silicon-Q-22 (SQ22) as a ...

    • Global, Regional, and National Burden of Nontraumatic Subarachnoid Hemorrhage: The Global Burden of Disease Study 2021. 

      Rautalin, Ilari; Volovici, Victor; Stark, Benjamin A; Johnson, Catherine O; Kaprio, Jaakko; ... more authors ( American Medical Association , 2025 , Article)
      Nontraumatic subarachnoid hemorrhage (SAH) represents the third most common stroke type with unique etiologies, risk factors, diagnostics, and treatments. Nevertheless, epidemiological studies often cluster SAH with other ...

    • Global, regional and national burden of dietary iron deficiency from 1990 to 2021: a Global Burden of Disease study. 

      Lee, Sooji; Son, Yejun; Hwang, Jiyoung; Kim, Min Seo; Shin, Jae Il; ... more authors ( Wiley , 2025 , Article)
      Although iron deficiency is well documented, less is known about dietary involvement in symptomatic iron deficiency manifesting in medical conditions. In this study, we quantified the global burden of dietary iron deficiency, ...

    • Utilization of Complementary Medicine Among Type 2 Diabetes Patients in Qatar: A Cross Sectional Study 

      abouelela, rasha salah; AlBashtawi, Joud; Al-Jaber, Hend; Chokor, Fatima Al Zahraa; Shaito, Abdullah; ... more authors ( Elsevier , 2025 , Article)
      BackgroundDiabetes Mellitus (DM) is a chronic metabolic disorder characterized by elevated blood glucose levels due to inadequate insulin production or ineffective insulin utilization. The prevalence of DM is rising globally, ...

    • Atypical presentation of TRPV3 variant: Cerebral palsy and intellectual disability without dermatologic features of olmsted syndrome 

      Khoodoruth, Mohamed Adil Shah; Chut-kai Khoodoruth, Widaad Nuzhah; Khan, Yasser Saeed ( Elsevier , 2025 , Article)
      To the Editor: Olmsted syndrome (OS) is a rare genodermatosis, with limited cases reported globally, primarily characterized by progressive palmoplantar keratoderma and keratotic plaques, and is linked to mutations in the ...

    • Basophil-VAMP7 is a vital regulator of skin barrier integrity and chronic itch 

      Zhang, Wenhao; Dai, Xiaolong; Chen, Weiwei; Li, Yanqing; Mei, Huiyuan; ... more authors ( Elsevier , 2025 , Article)
      BackgroundAtopic dermatitis (AD) is a multifaceted inflammatory skin disease characterized by chronic itch and acute itch flare (AIF), with basophils playing pivotal roles in both. VAMP7 mediates immune responses; however, ...

    • In-Hospital Outcomes and Temporal Trends of Surgical Versus Intravascular Ultrasound–Guided Endovascular Interventions for Femoropopliteal Disease 

      Elsayed, Basel; Subahi, Ahmed; Sattar, Hamid; Abdelaziz, Amged; Mohamed, Tahir; ... more authors ( Elsevier , 2025 , Article)
      BackgroundPeripheral artery disease is a global health concern, with femoropopliteal disease being a common manifestation. Recent advancements in endovascular interventions (EVI), guided by intravascular ultrasound (IVUS), ...

    • Intracranial extension of parotid adenoid cystic carcinoma presenting as trigeminal neuralgia: A case report 

      Hassouneh, Ammar; Sawafta, Omar; Jaber, Osama; Ali, Abd Alkarim; Rahhal, Mhd Osama; ... more authors ( Elsevier , 2025 , Article)
      Being rare malignancies, parotid gland adenocarcinomas are most significantly represented by the ACC subtype due to their aggressive nature and propensity for PNI. We present a case of a 56-year-old male with right-sided ...

    • Long-term changes in lipid indices following Roux-en-Y gastric bypass: a meta-analysis 

      Jamialahamdi, Tannaz; Mirhadi, Elaheh; Abdalla, Mohammed A.; Gadde, Kishore M.; Almahmeed, Wael; ... more authors ( Springer , 2025 , Article)
      Introduction: Bariatric surgery yields clinically significant long-term weight loss accompanied by marked improvements in numerous weight-related comorbidities including type 2 diabetes, hypertension, dyslipidemia, obstructive ...

    • Rhus coriaria (Sumac) induces autophagic cell death and inhibits mTOR, p38MAPK and STAT3 pathways in 5fluorouracil-resistant colorectal cancer cells 

      Nizami, Zohra Nausheen; Al Azzani, Mazoun; Khaldi, Samah; Wali, Adil Farooq; Magramane, Rym; ... more authors ( Frontiers Media , 2025 , Article)
      Introduction: Colorectal cancer is a leading cause of cancer related-death worldwide, and resistance to 5-fluorouracil (5FU, a key component of chemotherapy regimens, is a major clinical concern. We have previously elucidated ...

    • Predictive performance of noninvasive factors for liver fibrosis in severe obesity: a screening based on machine learning models 

      Jamialahmadi, Tannaz; Looha, Mehdi Azizmohammad; Jangjoo, Sara; Emami, Nima; Abdalla, Mohammed Altigani; ... more authors ( Springer , 2025 , Article)
      Objectives: Liver fibrosis resulting from nonalcoholic fatty liver disease (NAFLD) and metabolic disorders is highly prevalent in patients with severe obesity and poses a significant health challenge. However, there is a ...

    • Revolutionizing hypertension treatment: aprocitentan’s dual action against resistant hypertension 

      Sahebkar, Amirhossein; Eid, Ali H. ( Taylor and Francis Group , 2025 , Article)
      Hypertension (HTN) significantly contributes to worldwide morbidity and mortality [Citation1,Citation2]. It impacts around 1.3 billion individuals globally, rendering it one of the most prevalent cardiovascular diseases ...

    • Liver Transplantation for Non-hepatocellular Carcinoma: The Role of Immune Checkpoint Inhibitors 

      Pegah, Bahrami; Al Zein, Mohammad; Eid, Ali H.; Sahebkar, Amirhossein ( Elsevier , 2025 , Article Review)
      Colorectal cancer (CRC), gastroenteropancreatic neuroendocrine neoplasm (GEP-NEN), and cholangiocarcinoma (CCA) exhibit high rates of morbidity and mortality once metastasized to the liver. Liver transplantation (LT) is a ...

    • Pharmacological Frontiers: The Rise of Selective NaV1.8 Inhibition for Pain Management 

      Eid, Ali H. ( Springer , 2025 , Article)
      Pain is a multifaceted disorder encompassing sensory, emotional, and cognitive dimensions. It presents a ubiquitous challenge to human health and well-being, demanding effective and safe management strategies [1]. Various ...

    • Impact of pomegranate juice consumption on glycemic indices: a systematic review and meta-analysis 

      Ghaemi, Fatemeh; Emadzadeh, Maryam; Eid, Ali H.; Jamialahmadi, Tannaz; Sahebkar, Amirhossein ( Emerald Publishing , 2025 , Article)
      Purpose: The purpose of this meta-analysis was to examine the effect of pomegranate juice (PJ) intake on glycemic control in adults. Design/methodology/approach: Materials and methods: PubMed (Medline), ISI Web of Science, ...

    • Precision meets repurposing: Innovative approaches in human papillomavirus and Epstein-Barr virus-driven cancer therapy 

      Fernandes, Queenie ( Elsevier , 2024 , Article)
      Viral malignancies represent a distinct entity among cancers. Oncoviruses like the Human Papilloma Virus (HPV) and the Epstein Barr Virus (EBV) are highly potent inducers of oncogenic transformation leading to tumor ...