A single tube system for the detection of Mycobacterium tuberculosis DNA using gold nanoparticles based FRET assay

Thumbnail
View/Open
Date
2017-08-31
Author
Amira, Mansour
Tammam, Salma
Althani, Asma
Azzazy, Hassan M.E.
Metadata
Show full item record
Abstract
The global combat against MTB is limited by challenges in accurate affordable detection. In this study, a rapid, affordable, single tube system for detection of unamplified MTB16s rDNA was developed. Utilizing a AuNP based FRET system, this assay achieved a sensitivity and specificity of 98.6% and 90% respectively.
URI
https://www.sciencedirect.com/science/article/pii/S0167701217301495
DOI/handle
http://dx.doi.org/10.1016/j.mimet.2017.06.001
http://hdl.handle.net/10576/44648
Collections