Browsing Biomedical Research Center Research by Author "Elrayess, Mohamed A"
Now showing items 1-20 of 56
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Age and sport intensity-dependent changes in cytokines and telomere length in elite athletes
Sellami, Maha; Al-Muraikhy, Shamma; Al-Jaber, Hend; Al-Amri, Hadaia; Al-Mansoori, Layla; Mazloum, Nayef A.; Donati, Francesco; Botre, Francesco; Elrayess, Mohamed A.... more authors ... less authors ( MDPI , 2021 , Article Review)Background: Exercise-associated immune response plays a crucial role in the aging process. The aim of this study is to investigate the effect of sport intensity on cytokine levels, oxidative stress markers and telomere ... -
Amniotic stem cells as a source of regenerative medicine to treat female infertility
Naeem, Aisha; Gupta, Nikita; Naeem, Usra; Elrayess, Mohamed A.; Albanese, Chris ( Springer , 2022 , Article Review)Impaired reproductive health is a worldwide problem that affects the psychological well-being of a society. Despite the technological developments to treat infertility, the global infertility rate is increasing significantly. ... -
apoA2 correlates to gestational age with decreased apolipoproteins A2, C1, C3 and E in gestational diabetes.
Ramanjaneya, Manjunath; Butler, Alexandra E; Bashir, Mohammed; Bettahi, Ilham; Moin, Abu Saleh Md; Ahmed, Lina; Elrayess, Mohamed A; Hunt, Steven C; Atkin, Stephen L; Abou-Samra, Abdul Badi... more authors ... less authors ( BMJ Publishing Group , 2021 , Article)Pregnant women with gestational diabetes mellitus (GDM) are at risk of adverse outcomes, including gestational hypertension, pre-eclampsia, and preterm delivery. This study was undertaken to determine if apolipoprotein ... -
Arrhythmia-Associated Calmodulin E105A Mutation Alters the Binding Affinity of CaM to a Ryanodine Receptor 2 CaM-Binding Pocket
Thanassoulas, Angelos; Theodoridou, Maria; Barrak, Laila; Riguene, Emna; Alyaarabi, Tamader; Elrayess, Mohamed A.; Lai, F. Anthony; Nomikos, Michail... more authors ... less authors ( MDPI , 2023 , Article)Calmodulin (CaM) is a small, multifunctional calcium (Ca2+)-binding sensor that binds and regulates the open probability of cardiac ryanodine receptor 2 (RyR2) at both low and high cytosolic Ca2+ concentrations. Recent ... -
Assessment of Serum Cytokines and Oxidative Stress Markers in Elite Athletes Reveals Unique Profiles Associated With Different Sport Disciplines
Sohail, Muhammad U.; Al-Mansoori, Layla; Al-Jaber, Hend; Georgakopoulos, Costas; Donati, Francesco; Botrè, Francesco; Sellami, Maha; Elrayess, Mohamed A.... more authors ... less authors ( Frontiers Media , 2020 , Article)© Copyright © 2020 Sohail, Al-Mansoori, Al-Jaber, Georgakopoulos, Donati, Botrè, Sellami and Elrayess. Objectives: Circulating cytokines and oxidative stress markers vary in response to different exercise regimens. This ... -
Association of Complement-Related Proteins in Subjects With and Without Second Trimester Gestational Diabetes.
Ramanjaneya, Manjunath; Butler, Alexandra E; Alkasem, Meis; Bashir, Mohammed; Jerobin, Jayakumar; Godwin, Angela; Moin, Abu Saleh Md; Ahmed, Lina; Elrayess, Mohamed A; Hunt, Steven C; Atkin, Stephen L; Abou-Samra, Abdul-Badi... more authors ... less authors ( Frontiers Media , 2021 , Article)Gestational Diabetes Mellitus (GDM) development is related to underlying metabolic syndrome that is associated with elevated complement C3 and C4. Elevated C3 levels have been associated with preeclampsia and the development ... -
The association of HFE gene H63D polymorphism with endurance athlete status and aerobic capacity: novel findings and a meta-analysis.
Semenova, Ekaterina A; Miyamoto-Mikami, Eri; Akimov, Egor B; Al-Khelaifi, Fatima; Murakami, Haruka; Zempo, Hirofumi; Kostryukova, Elena S; Kulemin, Nikolay A; Larin, Andrey K; Borisov, Oleg V; Miyachi, Motohiko; Popov, Daniil V; Boulygina, Eugenia A; Takaragawa, Mizuki; Kumagai, Hiroshi; Naito, Hisashi; Pushkarev, Vladimir P; Dyatlov, Dmitry A; Lekontsev, Eugene V; Pushkareva, Yuliya E; Andryushchenko, Liliya B; Elrayess, Mohamed A; Generozov, Edward V; Fuku, Noriyuki; Ahmetov, Ildus I... more authors ... less authors ( Springer , 2020 , Article)Iron is an important component of the oxygen-binding proteins and may be critical to optimal athletic performance. Previous studies have suggested that the G allele of C/G rare variant (rs1799945), which causes H63D amino ... -
Comparing Levels of Metabolic Predictors of Coronary Heart Disease between Healthy Lean and Overweight Females.
Abu-El-Ruz, Rasha; Abdel-Rahman, Manar E; Atkin, Stephen L; Elrayess, Mohamed A ( MDPI , 2021 , Article)Screening for the metabolomic signature of coronary heart disease (CHD) before disease onset could help in early diagnosis and potentially disease prevention. In this study, the levels of 17 CHD metabolic biomarkers in ... -
Comparing metabolic profiles between female endurance athletes and non-athletes reveals differences in androgen and corticosteroid levels
Amneh H., Tarkhan; Anwardeen, Najeha R.; Sellami, Maha; Donati, Francesco; Botrè, Francesco; de la Torre, Xavier; Elrayess, Mohamed A.... more authors ... less authors ( Elsevier , 2022 , Article)Endurance training is associated with physiological changes in elite athletes, but little is known about female-specific effects of endurance training. Despite the significant rise in female sports participation, findings ... -
Comparing the Metabolic Profiles Associated with Fitness Status between Insulin-Sensitive and Insulin-Resistant Non-Obese Individuals
AlMuraikhy, Shamma; Anwardeen, Najeha; Naeem, Aisha; Sellami, Maha; Domling, Alexander; Agouni, Abdelali; Elrayess, Mohamed A... more authors ... less authors ( MDPI , 2022 , Article)(1) Background: Young non-obese insulin-resistant (IR) individuals could be at risk of developing metabolic diseases including type 2 diabetes mellitus. The protective effect of physical activity in this apparently healthy ... -
A comparison of isolation and culture protocols for human amniotic mesenchymal stem cells.
Naeem, Aisha; Gupta, Nikita; Naeem, Usra; Khan, Muhammad Jawad; Elrayess, Mohamed A; Cui, Wanxing; Albanese, Chris... more authors ... less authors ( Taylor and Francis , 2022 , Article Review)The successful translation of mesenchymal stem cells (MSCs) from bench to bedside is predicated upon their regenerative capabilities and immunomodulatory potential. Many challenges still exist in making MSCs a viable and ... -
Corrigendum: Association of Complement-Related Proteins in Subjects With and Without Second Trimester Gestational Diabetes (Front. Endocrinol., (2021), 12, (641361), 10.3389/fendo.2021.641361)
Ramanjaneya, Manjunath; Butler, Alexandra E.; Alkasem, Meis; Bashir, Mohammed; Jerobin, Jayakumar; Godwin, Angela; Moin, Abu Saleh Md; Ahmed, Lina; Elrayess, Mohamed A.; Hunt, Steven C.; Atkin, Stephen L.; Abou-Samra, Abdul Badi... more authors ... less authors ( Frontiers Media S.A. , 2021 , Other)In the original article, there was an error. One of the funders wasmissed out in the Acknowledgements. A correction has been made to the Acknowledgements section. “The authors would like to thank Qatar Metabolic Institute, ... -
Editorial: OMICS-based approaches in sports research volume II.
Elrayess, Mohamed A; Botrè, Francesco; Palermo, Amelia ( Frontiers Media , 2022 , Other)OMICS approaches, including genomics, epigenomics, transcriptomics, proteomics, and metabolomics, continue to provide invaluable tools for better understanding of the molecular mechanisms underlying various physiological ... -
Editorial: OMICS-Based Approaches in Sports Research.
Elrayess, Mohamed A; Botrè, Francesco; Palermo, Amelia ( Frontiers Media , 2022 , Other)Genomics, transcriptomics and metabolomics are increasingly generating key insights for the development of precision approaches in heath and disease. Omics technologies have unlocked the high-throughput discovery of ... -
Effect of sera from elite athletes on cytokine secretion and insulin signaling in preadipocytes and skeletal muscle cells
Alheidous, Sara; Al-Muraikhy, Shamma; Rizk, Nasser; Sellami, Maha; Donati, Francesco; Botre, Francesco; Al-Mansoori, Layla; Elrayess, Mohamed A.... more authors ... less authors ( Frontiers Media , 2022 , Article)Introduction: The immunomodulatory effect of physical activity can impact insulin signaling differentially in adipose tissues and skeletal muscle cells, depending on sport intensity. In this study, the effect of serum from ... -
Elevated Adipsin and Reduced C5a Levels in the Maternal Serum and Follicular Fluid During Implantation Are Associated With Successful Pregnancy in Obese Women
Ramanjaneya, Manjunath; Diboun, Ilhame; Rizwana, Najeha; Dajani, Yaser; Ahmed, Lina; Butler, Alexandra E.; Almarzooqi, Thoraya Ali; Shahata, Mohammed; Al Bader, Moza Khalaf; Elgassim, Einas; Burjaq, Hasan; Atkin, Stephen L.; Abou-Samra, Abdul Badi; Elrayess, Mohamed A.... more authors ... less authors ( Frontiers Media , 2022 , Article)Introduction: Complement factors mediate the recruitment and activation of immune cells and are associated with metabolic changes during pregnancy. The aim of this study was to determine whether complement factors in the ... -
Evaluation of the Influence of Eggshell (ES) Concentration on the Degradation Behavior of Mg–2.5Zn Biodegradable Alloy in Simulated Body Fluid
Radwan, A. Bahgat; Okonkwo, Paul C.; Murugan, Srinivasan; Parande, Gururaj; Taryba, Maryna; Montemor, M. Fatima; Al-Mansoori, Layla; Elrayess, Mohamed A.; Al-Qahtani, Noora; Gupta, Manoj; Youssef, Khaled M.; Case, Raymundo; Shakoor, R. A.; Abdullah, Aboubakr M.... more authors ... less authors ( American Chemical Society (ACS) , 2023 , Article)Currently, permanent vascular stents are fabricated using titanium and stainless steel implants that are nondegradable and offer high stability, but they have certain disadvantages. For example, the prolonged exposition ... -
Exercise Metabolome: Insights for Health and Performance
Jaguri, Aayami; Al Thani, Asmaa A.; Elrayess, Mohamed A. ( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)Exercise has many benefits for physical and mental well-being. Metabolomics research has allowed scientists to study the impact of exercise on the body by analyzing metabolites released by tissues such as skeletal muscle, ... -
From an Apple to a Pear: Moving Fat around for Reversing Insulin Resistance.
Alser, Maha; Elrayess, Mohamed A ( MDPI , 2022 , Article Review)Type 2 diabetes (T2D) is a chronic condition where the body is resistant to insulin, leading to an elevated blood glucose state. Obesity is a main factor leading to T2D. Many clinical studies, however, have described a ... -
GATA-3 as a potential therapeutic target for insulin resistance and type 2 diabetes mellitus.
Al-Jaber, Hend; Al-Mansoori, Layla; Elrayess, Mohamed A ( PubMed Central , 2020 , Article Review)Impaired adipogenesis plays an important role in the development of obesity-associated insulin resistance and type 2 diabetes as it leads to ectopic fat deposition. The anti-adipogenic transcription factor GATA-3 was ...