Search
Now showing items 1-10 of 144
Design, synthesis, and validation of novel nitrogen-based chalcone analogs against triple negative breast cancer
(
Elsevier Masson s.r.l.
, 2020 , Article)
Great strides have been made in triple negative breast cancer (TNBC) treatment, which represents 20% of total predicted annual US breast cancer (BC) cases. Despite the development of several therapeutics, TNBC patients ...
Novel polymethoxylated chalcones as potential compounds against kras-mutant colorectal cancers
(
Bentham Science Publishers
, 2020 , Article)
Background/Objective: KRAS-mutant colorectal cancers (CRC) are tumors that are associated with poor prognosis. However, no effective treatments are available to target them. Therefore, we designed and synthesized novel ...
E-cadherin/catenin complex modulations in human oral cancer
(
Springer Netherlands
, 2015 , Book chapter)
Oral cancer is a common neoplasm in both male and female worldwide; the incidence and mortality of this cancer have increased over the past decades. Cancer metastasis is a major cause of morbidity and mortality in oral ...
Crosstalk between Microglia and Neurons in Neurotrauma: An Overview of the Underlying Mechanisms.
(
Bentham Science Publishers
, 2022 , Article Review)
Microglia are the resident immune cells of the brain and play a crucial role in housekeeping and maintaining homeostasis of the brain microenvironment. Upon injury or disease, microglial cells become activated, at least ...
A comprehensive review summarizing the recent biomedical applications of functionalized carbon nanofibers
(
John Wiley and Sons Inc
, 2021 , Article)
Since the discovery and fabrication of carbon nanofibers (CNFs) over a decade ago, scientists foster to discover novel myriad potential applications for this material in both biomedicine and industry. The unique economic ...
mRNA-1273 COVID-19 vaccine effectiveness against the B.1.1.7 and B.1.351 variants and severe COVID-19 disease in Qatar
(2021 , Article)
The SARS-CoV-2 pandemic continues to be a global health concern. The mRNA-1273 (Moderna) vaccine was reported to have an efficacy of 94.1% at preventing symptomatic COVID-19 due to infection with ‘wild-type’ variants in a ...
Understanding diabetes-induced cardiomyopathy from the perspective of renin angiotensin aldosterone system
(
Springer
, 2021 , Article)
Experimental and clinical evidence suggests that diabetic subjects are predisposed to a distinct cardiovascular dysfunction, known as diabetic cardiomyopathy (DCM), which could be an autonomous disease independent of ...
The Spectrum of Antibiotic Prescribing during COVID-19 Pandemic: A Systematic Literature Review
(
Mary Ann Liebert Inc.
, 2021 , Article Review)
Objectives: Over the last decades, there has been a significant increase in antimicrobial prescribing and consumption associated with the development of patients' adverse events and antimicrobial resistance (AMR) to the ...
The stereological, immunohistological, and gene expression studies in an infected ischemic wound in diabetic rats treated by human adipose-derived stem cells and photobiomodulation
(
Institute for Ionics
, 2023 , Article)
We investigated the impacts of photobiomodulation (PBM) and human allogeneic adipose-derived stem cells (ha-ADS) together and or alone applications on the stereological parameters, immunohistochemical characterizing of M1 ...
Multifunctional Bioactive Scaffolds from ARX- g-(Zn@rGO)-HAp for Bone Tissue Engineering: In Vitro Antibacterial, Antitumor, and Biocompatibility Evaluations
(
American Chemical Society
, 2022 , Article)
Advanced biomaterials are required with enhanced antibacterial and anticancer activities to obtain desirable biocompatibility during and after scaffold implantation in tissue engineering. Here, we report the development ...