Search

Now showing items 1-4 of 4

Ethanolic extract of Origanum syriacum L. leaves exhibits potent anti-breast cancer potential and robust antioxidant properties

Mesmar, Joelle; Abdallah, Rola; Hamade, Kamar; Baydoun, Serine; Al-Thani, Najlaa; ... more authors ... less authors ( Frontiers Media , 2022 , Article)

Background: Breast cancer (BC) is the second most common cancer overall. In women, BC is the most prevalent cancer and the leading cause of cancer-related mortality. Triple-negative BC (TNBC) is the most aggressive BC, ...

Origanum syriacum L. Attenuates the Malignant Phenotype of MDA-MB231 Breast Cancer Cells

AlKahlout, Amal; Fardoun, Manal; Mesmar, Joelle; Abdallah, Rola; Badran, Adnan; ... more authors ... less authors ( Frontiers Media , 2022 , Article)

Breast cancer is the leading cause of cancer-related deaths among women. Among breast cancer types, triple negative breast cancer (TNBC) is the most aggressive, and is resistant to hormonal and chemotherapeutic treatments. ...

Ubiquitin-Related Modifier 1 (URM-1) Modulates Cx43 in Breast Cancer Cell Lines.

El-Hajjar, Layal; Saliba, Jessica; Karam, Mario; Shaito, Abdullah; El Hajj, Hiba; ... more authors ... less authors ( MDPI , 2023 , Article)

Gap-junction-forming connexins are exquisitely regulated by post-translational modifications (PTMs). In particular, the PTM of connexin 43 (Cx43), a tumor suppressor protein, regulates its turnover and activity. Here, we ...

Ziziphus nummularia crude and fractionated extracts attenuate the malignant phenotype of human triple-negative breast cancer cells

Shaito, Abdullah; Abdallah, Rola; Sobeh, Mansour; Sahri, Nihad; Mesmar, Joelle E.; ... more authors ... less authors ( Symposium Cracoviense , 2024 , Conference Paper)

Triple negative breast cancer (TNBC) is the most aggressive subtype of breast cancer and has limited therapeutic options. Effects of Ziziphus nummularia against TNBC have not been investigated yet. An ethanolic extract of ...