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Combined chemo-magnetic field-photothermal breast cancer therapy based on porous magnetite nanospheres

Sharifi, Majid; Hasan, Anwarul; Nanakali, Nadir Mustafa Qadir; Salihi, Abbas; Qadir, Fikry Ali; ... more authors ... less authors ( Nature Research , 2020 , Article)

The efficacy of different modalities of treating breast cancer is inhibited by several limitations such as off-targeted drug distribution, rapid drug clearance, and drug resistance. To overcome these limitations, we developed ...

Crosstalk between HER2 and PD-1/PD-L1 in Breast Cancer: From Clinical Applications to Mathematical Models.

Padmanabhan, Regina; Kheraldine, Hadeel Shafeeq; Meskin, Nader; Vranic, Semir; Al Moustafa, Ala-Eddin ( Springer , 2020 , Article)

Breast cancer is one of the major causes of mortality in women worldwide. The most aggressive breast cancer subtypes are human epidermal growth factor receptor-positive (HER2) and triple-negative breast cancers. Therapies ...

Elaeagnus angustifolia Plant Extract Inhibits Epithelial-Mesenchymal Transition and Induces Apoptosis via HER2 Inactivation and JNK Pathway in HER2-Positive Breast Cancer Cells

Jabeen, Ayesha; Sharma, Anju; Gupta, Ishita; Kheraldine, Hadeel; Vranic, Semir; ... more authors ... less authors ( MDPI , 2020 , Article)

Elaeagnus angustifolia (EA) is a medicinal plant used for treating several human diseases in the Middle East. Meanwhile, the outcome of extract on HER2-positive breast cancer remains nascent. Thus, we herein investigated ...

Breast Cancer During Pregnancy: A Marked Propensity to Triple-Negative Phenotype.

Allouch, Soumaya; Gupta, Ishita; Malik, Shaza; Al Farsi, Halema F; Vranic, Semir; ... more authors ... less authors ( Frontiers Media , 2020 , Article)

Breast and cervical cancers comprise 50% of all cancers during pregnancy. In particular, gestational breast cancer is considered one of the most aggressive types of cancers, which is a rare but fatal disease. However, the ...