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المؤلفAhmed, Mustafa
المؤلفMaliyakkal, Abdul Majeed
تاريخ الإتاحة2023-08-05T11:56:21Z
تاريخ النشر2022-05-01
اسم المنشورCureus‏
المعرّفhttp://dx.doi.org/10.7759/cureus.25061
الاقتباسAhmed, M., & Maliyakkal, A. M. (2022). Non-ST-Segment Elevation Myocardial Infarction Shortly After Starting Steroid Replacement Therapy in a Patient With Adrenal Insufficiency. Cureus, 14(5).‏
معرّف المصادر الموحدhttp://hdl.handle.net/10576/46472
الملخصAdrenal insufficiency is a rare disorder that results from etiological factors affecting either the hypothalamic-pituitary axis or the adrenal gland itself. Studies have associated an inherently increased risk of cardiovascular events with this condition. It is treated with exogenous steroid supplementation. However, in recent years, there have been an increasing number of reports regarding the potential of steroid therapy to precipitate acute cardiac events. However, this risk is generally assumed to be dose-dependent and could be absent in patients receiving low-dose glucocorticoid treatment. We present a case of a 71-year-old woman who was admitted to our institution with bilateral lower limb swelling. Blood investigation revealed hypoalbuminemia and hyponatremia. Upon further evaluation she was diagnosed to have adrenal insufficiency and was started on hydrocortisone replacement therapy; however, the patient developed non-ST-segment elevation myocardial infarction (NSTEMI) and acute pulmonary edema a few days after starting steroid replacement therapy. Here, we discuss the possible association between hydrocortisone use and the development of acute cardiac events.
اللغةen
الموضوعadrenal insufficiency
cardiovascular risk
glucocorticoid replacement
hydrocortisone
st-elevation myocardial infarction (stemi)
العنوانNon-ST-Segment Elevation Myocardial Infarction Shortly After Starting Steroid Replacement Therapy in a Patient With Adrenal Insufficiency.
النوعArticle
dc.accessType Open Access


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