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AuthorAlsamri, Halima
AuthorAthamneh, Khawlah
AuthorPintus, Gianfranco
AuthorEid, Ali H.
AuthorIratni, Rabah
Available date2023-08-09T11:31:24Z
Publication Date2021-01-08
Publication NameAntioxidants
Identifierhttp://dx.doi.org/10.3390/antiox10010073
CitationAlsamri, H., Athamneh, K., Pintus, G., Eid, A. H., & Iratni, R. (2021). Pharmacological and antioxidant activities of Rhus coriaria L.(Sumac). Antioxidants, 10(1), 73.
URIhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85099421417&origin=inward
URIhttp://hdl.handle.net/10576/46605
AbstractRhus coriaria L. (Anacardiaceae), commonly known as sumac, is a commonly used spice, condiment, and flavoring agent, especially in the Mediterranean region. Owing to its bountiful beneficial values, sumac has been used in traditional medicine for the management and treatment of many ailments including hemorrhoids, wound healing, diarrhea, ulcer, and eye inflammation. This plant is rich in various classes of phytochemicals including flavonoids, tannins, polyphenolic com-pounds, organic acids, and many others. By virtue of its bioactive, Rhus coriaria possesses powerful antioxidant capacities that have ameliorative and therapeutic benefits for many common diseases including cardiovascular disease, diabetes, and cancer. This review describes the phytochemical properties of R. coriaria and then focuses on the potent antioxidant capacities of sumac. We then dissect the cellular and molecular mechanisms of sumac’s action in modulating many pathophysi-ological instigators. We show how accumulating evidence supports the antibacterial, antinocicep-tive, antidiabetic, cardioprotective, neuroprotective, and anticancer effects of this plant, especially that toxicity studies show that sumac is very safe to consume by humans and has little toxicity. Taken together, the findings we summarize here support the utilization of this plant as an attractive target for drug discovery.
SponsorThis work was supported by the UAEU Program for Advanced Research (grant no. 31S111-UPAR) to RI.
Languageen
PublisherMultidisciplinary Digital Publishing Institute (MDPI)
SubjectAnticancer
Antimicrobial
Antioxidant
Phytochemical
Rhus coriaria
TitlePharmacological and antioxidant activities of rhus coriaria l. (sumac)
TypeArticle
Issue Number1
Volume Number10
ESSN2076-3921
dc.accessType Open Access


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