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AuthorMubasher, Mahmood
AuthorSyed, Tausif
AuthorHanafi, Amir
AuthorYu, Zhao
AuthorYusuf, Ibrahim
AuthorAbdullah, Abdullah Sayied
AuthorMohamed, Mouhand F.H.
AuthorAlweis, Richard
AuthorRao, Mohan
AuthorHoefen, Ryan
AuthorDanjuma, Mohammed I.
Available date2023-08-31T17:46:19Z
Publication Date2020-10-28
Publication NameClinical Medicine Insights: Cardiology
Identifierhttp://dx.doi.org/10.1177/1179546820955179
CitationMubasher, M., Syed, T., Hanafi, A., Yu, Z., Yusuf, I., Abdullah, A. S., ... & Danjuma, M. I. (2020). An investigation into the association between inflammatory bowel disease and cardiac arrhythmias: an examination of the United States national inpatient sample database. Clinical Medicine Insights: Cardiology, 14, 1179546820955179.
URIhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85094667250&origin=inward
URIhttp://hdl.handle.net/10576/47149
AbstractBackground: Inflammatory bowel diseases (IBD) associated-chronic inflammation and autonomic dysregulation may predispose to arrhythmias. However, its exact prevalence is unknown. Thus, we aimed to ascertain the prevalence of arrhythmias in patients with IBD. Methods: We queried the Nationwide Inpatient Sample (the largest publicly available all-payer inpatient USA database) from 2012 to 2014. We used the International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9 CM) discharge codes to identify adult patients (⩾18 years) with IBD and dysrhythmias (supraventricular tachycardia (SVT), atrial fibrillation, atrial flutter, ventricular tachycardia (VT), or ventricular fibrillation). Furthermore, we identified risk factors for cardiovascular disease. We divided patients into 2 cohorts, IBD cohorts, and non-IBD cohort. The independent effect of a diagnosis of IBD on the risk of dysrhythmias was examined using a multivariable logistic regression model controlling for multiple confounders. Results: We identified 847 235 and 84 757 349 weighted hospitalizations among patients with IBD and non-IBD cohorts, respectively. Patients with IBD were less likely to be hospitalized for dysrhythmias than the non-IBD (9.7% vs 14.2%, P <.001). The hospitalization odds for dysrhythmias among patients with IBD were less than the general population (OR 0.87; 95% CI 0.85-0.88). However, the prevalence of SVT and VT was indifferent between the 2 groups. Male sex, age of over 60, and white race were risk factors for dysrhythmias. Conclusion: Despite prior reports of a higher prevalence of arrhythmias among patients with IBD, in a nationwide inpatient database, we found lower rates of hospitalization-related-arrhythmias in the IBD population compared to that of the general population.
SponsorWe acknowledge the Qatar National Library (QNL) for funding the open access publication of this article.
Languageen
PublisherSAGE Publications
Subjectarrhythmias
Crohn’s disease
Inflammatory bowel disease
Nationwide Inpatient Sample
ulcerative colitis
TitleAn Investigation into the Association Between Inflammatory Bowel Disease and Cardiac Arrhythmias: An Examination of the United States National Inpatient Sample Database
TypeArticle
Volume Number14
ESSN1179-5468
dc.accessType Open Access


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