Browsing Biomedical Sciences by Title
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Macrophage Infection by Mycobacteria
( OMICS International , 2016 , Article)Mycobacterium tuberculosis is the etiological agent of tuberculosis. It is a pathogen that continues to draw international concerns particularly due to the emergence of multi-drug resistance and to the difficulties ... -
Management of chronic myeloid leukaemia: current treatment options, challenges, and future strategies.
( taylor and francis online , 2023 , Article)Small molecule therapy is a critical component of targeted anticancer treatment, with tyrosine kinase inhibitors (TKIs) being the first compounds to treat the clonal Chronic Myelogenous Leukaemia (CML) translocation t ... -
Mangifera indica L. kernel ethanol extract inhibits cell viability and proliferation with induction of cell cycle arrest and apoptosis in lung cancer cells
( Taylor and Francis Ltd. , 2024 , Article)In this study, we investigated the effects of an ethanolic extract of Mangifera indica L. kernel on the viability and proliferation of human lung cancer cells. We utilized MTT and BrdU cell proliferation assays, morphological ... -
The march of pluripotent stem cells in cardiovascular regenerative medicine.
( BMC , 2018 , Article Review)Cardiovascular disease (CVD) continues to be the leading cause of global morbidity and mortality. Heart failure remains a major contributor to this mortality. Despite major therapeutic advances over the past decades, a ... -
Marjoram Relaxes Rat Thoracic Aorta Via a PI3-K/eNOS/cGMP Pathway.
( MDPI , 2019 , Article)Despite pharmacotherapeutic advances, cardiovascular disease (CVD) remains the primary cause of global mortality. Alternative approaches, such as herbal medicine, continue to be sought to reduce this burden. is recognized ... -
Markers associated with covid-19 susceptibility, resistance, and severity
( MDPI AG , 2021 , Article Review)In December 2019, the latest member of the coronavirus family, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), emerged in Wuhan, China, leading to the outbreak of an unusual viral pneumonia known as coronavirus ... -
Mass Spectrometry, Structural Analysis, and Anti-Inflammatory Properties of Photo-Cross-Linked Human Albumin Hydrogels
( American Chemical Society , 2022 , Article)Albumin-based hydrogels offer unique benefits such as biodegradability and high binding affinity to various biomolecules, which make them suitable candidates for biomedical applications. Here, we report a non-immunogenic ... -
Material modeling and recent findings in transcatheter aortic valve implantation simulations
( Elsevier , 2024 , Article Review)Background and objective: Transcatheter aortic valve implantation (TAVI) has significantly transformed the management of aortic valve (AV) diseases, presenting a minimally invasive option compared to traditional surgical ... -
Maternal microbiota regulate glucocorticoids levels and placental development in mice
( bioscientifica , 2015 , Conference Proceedings)The gut microbiota contributes to postnatal development and maturation by influencing barrier functions of the intestinal wall, the development of the immune system, and the utilisation of nutrients. Recent studies have ... -
Measuring influenza hemagglutinin (HA) stem-specific antibody-dependent cellular cytotoxicity (ADCC) in human sera using novel stabilized stem nanoparticle probes
( Elsevier , 2020 , Article)Background: Generating vaccine that confers a complete protection is a major goal in designing a universal influenza vaccine. Currently, there is a considerable interest in the broadly neutralizing antibodies (bnAb) targeting ... -
Medicinal properties of Qatari wetland plants: A review
( AkiNik Publications , 2024 , Article)For over 60,000 years, human dependence on herbal remedies has been a cornerstone of traditional medicine. However, recent times have witnessed escalating concerns about the sustainability of these practices, especially ... -
Mendelian inheritance of trimodal CpG methylation sites suggests distal cis-acting genetic effects.
( BioMed Central , 2016 , Article)Environmentally influenced phenotypes, such as obesity and insulin resistance, can be transmitted over multiple generations. Epigenetic modifications, such as methylation of DNA cytosine-guanine (CpG) pairs, may be carriers ... -
Meta-analysis of the incidence of lead dislodgement with conventional and leadless pacemaker systems
( Blackwell Publishing Inc. , 2018 , Article Review)Introduction Leadless cardiac pacemaker (LCP) implantation using a transcatheter was recently developed to avoid pocket- and lead-related complications. Although a LCP has an active fixation mechanism using tines or a ... -
Metabolic shift toward oxidative phosphorylation in docetaxel resistant prostate cancer cells
( Impact Journals , 2016 , Article)Drug resistance of cancer cells is recognized as the primary cause of failure of chemotherapeutic treatment in most human cancers. Growing evidences support the idea that deregulated cellular metabolism is linked to such ... -
Metabolic Signatures of Type 2 Diabetes Mellitus and Hypertension in COVID-19 Patients With Different Disease Severity.
( Frontiers Media , 2022 , Article)Increased COVID-19 disease severity is higher among patients with type 2 diabetes mellitus and hypertension. However, the metabolic pathways underlying this association are not fully characterized. This study aims to ... -
The Metabolic Switch of Physical Activity in Non-Obese Insulin Resistant Individuals.
( MDPI , 2023 , Article)Healthy non-obese insulin resistant (IR) individuals are at higher risk of metabolic syndrome. The metabolic signature of the increased risk was previously determined. Physical activity can lower the risk of insulin ... -
Metabolomic biomarkers of pancreatic cancer: a meta-analysis study
( Impact Journals , 2017 , Article)Pancreatic cancer (PC) is an aggressive disease with high mortality rates, however, there is no blood test for early detection and diagnosis of this disease. Several research groups have reported on metabolomics based ... -
Metabolomics Approaches for the Diagnosis, Treatment, and Better Disease Management of Viral Infections
( MDPI , 2023 , Article Review)Metabolomics is an analytical approach that involves profiling and comparing the metabolites present in biological samples. This scoping review article offers an overview of current metabolomics approaches and their ... -
Metagenomic Analysis of Oral Microbiome during pregnancy
( Qatar University Press , 2021 , Poster)Pregnancy is a dynamic physiological process associated with significant hormonal, immune and metabolic changes to support the growth and development of the fetus. Several studies have highlighted the role of gut microbiota ... -
Metformin and HER2-positive breast cancer: Mechanisms and therapeutic implications
( Elsevier , 2023 , Article)Due to the strong association between diabetes and cancer incidents, several anti-diabetic drugs, including metformin, have been examined for their anticancer activity. Metformin is a biguanide antihyperglycemic agent used ...
