Biomedical Sciences: Recent submissions
Now showing items 21-40 of 838
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Exploring endothelial dysfunction in major rheumatic diseases: current trends and future directions
( Springer Science and Business Media Deutschland GmbH , 2025 , Article Review)The relationship between rheumatic diseases (RDs) and endothelial dysfunction (ED) is intricate and multifaceted, with chronic inflammation and immune system dysregulation playing key roles. RDs, including Osteoarthritis ... -
Medicinal Phytocompounds as Potential Inhibitors of p300-HIF1? Interaction: A Structure-Based Screening and Molecular Dynamics Simulation Study
( Multidisciplinary Digital Publishing Institute (MDPI) , 2025 , Article)Background: Hypoxia plays a key role in cancer progression, mainly by stabilizing and activating hypoxia-inducible factor-1 (HIF-1). For HIF-1 to function under low oxygen conditions, it must interact with the transcriptional ... -
Protection conferred by SARS-CoV-2 infection across a spectrum of reinfection symptoms and severities
( BMJ Publishing Group , 2025 , Article)Background SARS-CoV-2 infection is associated with protection against reinfection. This study analysed this protection across different reinfection symptoms and severities, comparing the preomicron and omicron eras. Methods ... -
Integrating pharmacogenomics in three Middle Eastern countries' healthcare (Lebanon, Qatar, and Saudi Arabia): Current insights, challenges, and strategic directions
( Public Library of Science , 2025 , Article)Background and objectives Pharmacogenomics (PGx) leverages genomic information to tailor drug therapies, enhancing precision medicine. Despite global advancements, its implementation in Lebanon, Qatar, and Saudi Arabia ... -
Therapeutic potential and challenges of mesenchymal stem cells in neurological disorders: A concise analysis
( Oxford University Press , 2025 , Article)Neurological diseases comprise a wide array of conditions affecting both the central and peripheral nervous systems. Neurodegenerative diseases encompass a group of debilitating and often fatal neurological disorders for ... -
Spectrum of genetic variants associated with maple syrup urine disease in the Middle East, North Africa, and Türkiye (MENAT): a systematic review
( BioMed Central Ltd , 2025 , Article)Background Maple syrup urine disease (MSUD) is a hereditary metabolic disorder caused by a deficiency in the branched-chain α-keto acid dehydrogenase (BCKD) enzymatic complex. The Middle East and North Africa, and Türkiye ... -
Prevalence of hepatitis C virus infection in Qatar's resident population based on a national screening campaign
( Nature Research , 2025 , Article)Hepatitis C virus (HCV) infection poses a global health challenge, yet its epidemiology in Qatar remains underexplored. This study estimated HCV antibody (Ab) prevalence in Qatar and examined associated socio-demographic ... -
Artificial Intelligence in Bacterial Infections Control: A Scoping Review
( Multidisciplinary Digital Publishing Institute (MDPI) , 2025 , Article Review)Background/Objectives: Artificial intelligence has made significant strides in healthcare, contributing to diagnosing, treating, monitoring, preventing, and testing various diseases. Despite its broad adoption, clinical ... -
Accre 8 emerging point of care CLIA system for vitamin B12 assessment compared with three established assays
( Nature Research , 2025 , Article)Accurate Vitamin B12 (Vit B12) quantification is essential for diagnosing deficiencies linked to neurological and hematological disorders. The Accre 8 Point-of-Care (POC) Chemiluminescent Immunoassay (CLIA) system offers ... -
Indoleacetylglutamine Pathway Is a Potential Biomarker for Cardiovascular Diseases
( Multidisciplinary Digital Publishing Institute (MDPI) , 2025 , Article)Cardiovascular diseases (CVDs) remain a leading cause of global morbidity and mortality. Metabolomics allows for the identification of important biomarkers for CVDs, essential for early detection and risk assessment. This ... -
Silicone Quaterium-22 Surfactant as an Eco-Friendly Carbon Steel Anticorrosive: Assessment of Corrosion Inhibition Properties and Ecotoxicity in Zebrafish Embryos
( Elsevier , 2025 , Article)Corrosion of carbon steel pipelines in the oil and gas industry presents operational and environmental challenges, requiring safer alternatives to toxic corrosion inhibitors. This study evaluates Silicon-Q-22 (SQ22) as a ... -
Optimization of UAE of phenolic and antioxidant compounds from Ephedra foeminea by RSM
( Qatar University , 2025 , Poster)Ephedra foeminea Forssk, a widely distributed shrub in the East Mediterranean, possesses numerous traditional medicinal applications and is an abundant source of bioactive phytochemical metabolites. In this study, ult ... -
Utilization of Complementary Medicine Among Type 2 Diabetes Patients in Qatar: A Cross Sectional Study
( Elsevier , 2025 , Article)BackgroundDiabetes Mellitus (DM) is a chronic metabolic disorder characterized by elevated blood glucose levels due to inadequate insulin production or ineffective insulin utilization. The prevalence of DM is rising globally, ... -
Phytochemical Composition and Anticancer Properties of Haplophyllum tuberculatum Growing in Qatar and Oman Against Human Triple-Negative Breast Cancer Cells
( Qatar University , 2025 , Poster)Introduction: Breast cancer ranks as the most frequently diagnosed cancer globally, with the triple-negative breast cancer (TNBC) subtype linked to a notably poor prognosis. The absence of optimal therapeutic regimens ... -
Developmental toxicity of Peganum harmala seed extractsin zebrafish embryos
( Qatar University , 2025 , Poster)Introduction: Peganum harmala L. is a widely utilized plant in traditional medicine in many countries, including Qatar. Nevertheless, there have been several reports of toxic effects associated with the use of P. harmala ... -
Characterization of Anti-Cancer Properties of Qatari Prosopis Species, Prosopis juliflora and Prosopis cineraria, against Human Breast, Lung, and Ovarian Cancer Cell Lines
( Qatar University , 2025 , Poster)Background: The Prosopis plant species have been reported for their diverse therapeutic benefits, including anti-inflammatory, anti-microbial, antioxidant, and anti- tumor properties. Prosopis cineraria, Prosopis ... -
Efficient and Direct Route to 5-Iodo-4 H -Quinoxalines via Copper-Catalyzed Double C-N Arylations of 1,2,3-Triiodoarenes: Potential Application towards 5-Substituted 4 H -Quinoxalines
( Georg Thieme Verlag , 2024 , Article)A simple, direct, and regioselective protocol to substituted 5-iodo-4 H -quinoxalines through double C-N arylations of 1,2,3-triiodobenzenes and 1,2-diamines is reported. Remarkably, the N-arylation couplings proceed ... -
Intravenous administration of gold nanoparticles in rats exhibit alterations in sphingomyelins, bile acids, sphingolipids, and cholesterol esters levels
( Springer , 2025 , Article)Nanoparticles (NP) have gained significant attention in biomedical research due to their unique properties and potential applications in drug delivery, imaging, and diagnostics. Gold (AuNPs) and silver (AgNPs) NPs are among ... -
Associations between Bone Mineral Density and WOMAC Scores in Healthy Individuals: Insights from the Qatar Biobank
( Elsevier , 2025 , Article)Background: Bone mineral density (BMD) is an indicator of bone health that predicts future bone fractures. The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) is used to assess the severity of symptoms ... -
Eco-friendly pyridine-derivatives for corrosion inhibition of carbon steel during acidic treatments: mechanistic insights from electrochemical, surface, and computational studies
( Springer Nature , 2024 , Article)Pyridine and urea derivatives have emerged as valuable corrosion platforms ascribed to exceptional coordination potential, and environmental friendliness. Two novel structures of pyridine-carbamides (MS30 & MS31) were ...
