عرض بسيط للتسجيلة

المؤلفZaki, Hany
المؤلفTürkmen, Süha
المؤلفAzad, Aftab
المؤلفBashir, Khalid
المؤلفElmoheen, Amr
المؤلفShaban, Eman
المؤلفIftikhar, Haris
المؤلفShallik, Nabil
تاريخ الإتاحة2023-11-14T06:14:41Z
تاريخ النشر2023-04-01
اسم المنشورTurkish Journal of Emergency Medicine
المعرّفhttp://dx.doi.org/10.4103/tjem.tjem_229_22
الاقتباسZaki, H., Türkmen, S., Azad, A., Bashir, K., Elmoheen, A., Shaban, E., ... & Shallik, N. (2023). Clinical assessment and risk stratification for prehospital use of methoxyflurane versus standard analgesia in adult patients with trauma pain. Turkish Journal of Emergency Medicine, 23(2), 65.‏
معرّف المصادر الموحدhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85163176956&origin=inward
معرّف المصادر الموحدhttp://hdl.handle.net/10576/49223
الملخصOligoanalgesia, the undertreatment of trauma-related pain using standard analgesics in prehospital and emergency departments, has been extensively documented as one of the major challenges affecting the effective treatment of trauma-related pain. When administered in low doses, methoxyflurane has been highlighted by numerous medical works of literature to provide an effective, nonopioid, nonnarcotic treatment alternative to standard analgesics for prehospital and emergency department use. Low-dose methoxyflurane has been associated with fast-pain relief in adult patients manifesting moderate-to-severe pain symptoms. This systematic review and meta-analysis aimed to assess the clinical implication of low-dose methoxyflurane use in prehospital and emergency departments in adult patients with moderate-to-severe trauma-related pain. Moreover, the review aimed at assessing the risk stratification associated with using low-dose methoxyflurane in prehospital and emergency departments. The systematic review and meta-analysis performed a comprehensive search for pertinent literature assessing the implications and risks of using low-dose methoxyflurane in adult patients exhibiting moderate-to-severe trauma-related pain in prehospital settings. A comparison between the use of low-dose methoxyflurane and standard-of-care analgesics, placebo, in prehospital settings was reported in four clinically conducted randomized controlled trials (RCTs). These RCTs included the STOP! trial, InMEDIATE, MEDIATA, and the PenASAP trials. A meta-analysis comparing the time taken to achieve first pain relief on initial treatment of patients with moderate-to-severe trauma-related pain favored the use of low-dose methoxyflurane to the standard-of-care analgesics (mean difference = -6.63, 95% confidence interval = -7.37, -5.09) on time taken to establish effective pain relief. Low-dose methoxyflurane has been associated with superior and faster pain relief in prehospital and emergency departments in adult patients exhibiting moderate-to-severe trauma-related pain compared to other standard analgesics.
اللغةen
الناشرPMC
الموضوعAnalgesic
emergency
methoxyflurane
prehospital
traumatic pain
العنوانClinical assessment and risk stratification for prehospital use of methoxyflurane versus standard analgesia in adult patients with trauma pain
النوعArticle
رقم العدد2
رقم المجلد23
dc.accessType Abstract Only


الملفات في هذه التسجيلة

الملفاتالحجمالصيغةالعرض

لا توجد ملفات لها صلة بهذه التسجيلة.

هذه التسجيلة تظهر في المجموعات التالية

عرض بسيط للتسجيلة