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AuthorIbrahim, Wanis H.
AuthorAl-Shokri, Shaikha D.
AuthorHussein, Musa S.
AuthorAbu Afifeh, Lana M.
AuthorKaruppasamy, Gowri
AuthorParambil, Jessiya V.
AuthorElasad, Farras M.
AuthorFaris, Mohammed E.
AuthorAbdelghani, Mohamed S.
AuthorAbdellah, Ahmed
AuthorKamel, Antoun
AuthorGhazouani, Hafedh
AuthorAhmad, Mushtaq
AuthorAladab, Aisha
AuthorDanjuma, Mohammed I.
AuthorRaza, Tasleem
Available date2024-02-14T07:56:16Z
Publication Date2022-05-09
Publication NameQatar Medical Journal
Identifierhttp://dx.doi.org/10.5339/QMJ.2022.1
CitationH Ibrahim, W., Al-Shokri, S. D., Hussein, M. S., Abu Afifeh, L. M., Karuppasamy, G., Parambil, J. V., ... & Raza, T. (2022). Clinical, radiological, and outcome characteristics of acute pulmonary embolism: a 5-year experience from an academic tertiary center. Qatar Medical Journal, 2022(1), 1.
ISSN0253-8253
URIhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85133497844&origin=inward
URIhttp://hdl.handle.net/10576/51815
AbstractBackground: Acute pulmonary embolism (PE) is a common and potentially life-threatening condition. This comprehensive study from a Gulf Cooperation Council (GCC) country aimed to evaluate the clinical, radiological, and outcome characteristics associated with acute PE. Methods: This retrospective observational study analyzed data of patients with confirmed acute PE who were admitted to the largest academic tertiary center in the State of Qatar from January 1, 2014, to December 31, 2018. Data on the clinical presentation, radiologic, and echocardiographic findings, as well as outcomes were collected. Results: A total of 436 patients were diagnosed with acute PE during the study period (male, 53%). Approximately 56% of the patients were, 50 years old at presentation, with a median age of 47 years. In approximately 69% of cases, the PE occurred outside the hospital. The main associated comorbidities were obesity (34.6%), hypertension (29.4%), and diabetes (25%). Immobilization (25.9%) and recent surgery (20.6%) were the most common risk factors. The most frequent presenting symptom was dyspnea (39.5%), and the most frequent signs were tachycardia (49.8%) and tachypnea (45%). Cardiac arrest was the initial presentation in 2.2% of cases. Chest X-ray findings were normal in 41%. On computed tomography pulmonary angiography (CTPA), 41.3% of the patients had segmental PE, 37.1% had central PE, and 64.1% had bilateral PE. The main electrocardiographic (ECG) abnormality was sinus tachycardia (98%). In patients who underwent echocardiography, right ventricular (RV) enlargement was the main echocardiographic finding (36.4%). Low-, intermediate-, and high-risk PE constituted 49.8%, 31.4%, and 18.8% of the cases, respectively. Thrombolysis was prescribed in 8.3% of the total and 24.4% of the high-risk PE cases. Complications of PE and its treatment (from admission up to 6 months post-discharge) included minor bleeding (14%), major bleeding (5%), PE recurrence (4.8%), and chronic thromboembolic pulmonary hypertension (CTEPH) (5%). A total of 15 (3.4%) patients died from PE. Conclusions: Acute PE can manifest with complex and variable clinical and radiological syndromes. Striking findings in this study are the younger age of acute PE occurrence and the low PE-related mortality rate.
SponsorThe publication of this article was funded by the Medical Research Center at Hamad Medical Corporation.
Languageen
PublisherHBKU Press
Subjectclinical features
mortality
pulmonary embolism
Venous thromboembolism
TitleClinical, Radiological, and Outcome Characteristics of Acute Pulmonary Embolism: A 5-year Experience from an Academic Tertiary Center
TypeArticle
Issue Number1
Volume Number2022
ESSN2227-0426
dc.accessType Open Access


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