Show simple item record

AuthorRajagopal, Padma M.
AuthorSil, Satyam
AuthorDinesh, Prameela
AuthorShiju, Shilpa
AuthorArunkumar, D. P.
AuthorRamaiah, Srinivas S.
AuthorLalitha, Hande R.
AuthorMamatha, T.
AuthorKantinath, Ainapure P.
AuthorPujari, Lokesh
AuthorPradeep, B. S.
AuthorShenoy, Anusha B.
AuthorDesai, Anita
AuthorMunivenkatappa, Ashok
AuthorGudi, Chetan S.
AuthorBabu, Giridhara R.
AuthorSudarshan, M. K.
Available date2024-03-28T05:11:48Z
Publication Date2024-01-01
Publication NameIndian Journal of Community Medicine
Identifierhttp://dx.doi.org/10.4103/ijcm.ijcm_60_23
CitationRajagopal, P. M., Sil, S., Dinesh, P., Shiju, S., Arunkumar, D. P., Ramaiah, S. S., Lalitha, H. R., Mamatha, T., Kantinath, P. A., Pujari, L., Pradeep, B. S., Shenoy, A. B., Desai, A., Munivenkatappa, A., Gudi, C. S., Babu, G. R., & Sudarshan, M. K. (2024). Assessing the Burden of COVID-19 among Children Aged 6-14 Years in Karnataka, India: A Cross-sectional Survey. Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine, 49(1), 110–114. https://doi.org/10.4103/ijcm.ijcm_60_23
ISSN0970-0218
URIhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85182985004&origin=inward
URIhttp://hdl.handle.net/10576/53636
AbstractBackground: India experienced three coronavirus disease (COVID-19) waves, with the third attributed to the highly contagious Omicron variant. Before the national vaccination rollout for children above 6, understanding severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) immunoglobulin G (IgG) positivity in the pediatric population was essential. This study aims to assess the burden of Covid-19 infection and to estimate the seroprevalence in children aged 6 to 14 years in the state of Karnataka. Material and Methods: We surveyed 5,358 children aged 6-14 across Karnataka using 232 health facilities, from June 6 to 14, 2022. We determined the sample size using the PPS (Population Proportional to Size) technique and employed cluster sampling. We tested all participants for SARS-CoV-2 IgG with an enzyme-linked immunosorbent assay (ELISA) kit and SARS-CoV-2 RNA with reverse transcription-polymerase chain reaction (RT-PCR). We sequenced samples with a cycle threshold (CT) value below 25 using whole genomic sequencing (WGS). Result: We found an adjusted seroprevalence of IgG at 75.38% statewide, and we found 0.04% of children RT-PCR positive for COVID-19. We determined a case-to-infection ratio of 1:37 and identified the SARS-CoV-2 strains as Omicron, BA.5, and BA.2.10. Conclusion: The study showed a high seroprevalence of IgG among children with low active infection. Omicron, BA. 5, and BA. 2.10 variants were detected through WGS.
Languageen
PublisherMedknow Publications
SubjectAnti-SARS-CoV-2 IgG
COVID-19 antibody testing
Karnataka
pediatric serosurvey
TitleAssessing the Burden of COVID‑19 among Children Aged 6‑14 Years in Karnataka, India: A Cross‑sectional Survey
TypeArticle
Pagination110-114
Issue Number1
Volume Number49
ESSN1998-3581
dc.accessType Full Text


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record