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AuthorNaushad, Vamanjore A.
AuthorPurayil, Nishan K.
AuthorWilson, Godwin J.
AuthorChandra, Prem
AuthorJoseph, Prakash
AuthorKhalil, Zahida
AuthorZahid, Muhammad
AuthorKayakkool, Muhammed K.
AuthorShaik, NoorJahan
AuthorAyari, Basma
AuthorChalihadan, Sajid
AuthorElmagboul, Emad Basheir I.
AuthorDoiphode, Sanjay H.
Available date2024-07-22T09:19:58Z
Publication Date2022
Publication NameIJID Regions
ResourceScopus
Identifierhttp://dx.doi.org/10.1016/j.ijregi.2022.05.001
ISSN27727076
URIhttp://hdl.handle.net/10576/56903
AbstractBackground: Community-acquired urinary tract infection (UTI) is the most common infection caused by extended-spectrum beta-lactamase (ESBL)-producing organisms. Aim: to estimate the prevalence of ESBL-UTI in adults and to identify potential risk factors that may predispose to ESBL-UTI. Methods: A retrospective study involving adult patients with UTI caused by ESBL-producing organisms was undertaken. Patients with UTI caused by non-ESBL-producing organisms represented the control group. Results: In total, 1100 UTI isolates were included in the study, 277 of which were ESBL positive. The prevalence rate was 25.2%. The mean age of patients was 55.87 years. On univariate analysis, prior history of UTI or ESBL-UTI, invasive urological procedure within preceding 3 months, hospital admission within preceding 3 months, and exposure to antibiotics were found to be significant risk factors for ESBL-UTI. On multi-variate analysis, use of cephalosporins [adjusted odds ratio (OR) 1.61, P=0.048], previous ESBL-UTI (adjusted OR 2.67, P<0.001), and invasive urological procedure in the preceding year (adjusted OR 1.61, P=0.022) were found to be independent risk factors for ESBL-UTI. Conclusions: In Qatar, the prevalence of ESBL-UTI in adults is modest. Recent exposure to antibiotics, previous ESBL-UTI and invasive urological procedures were found to be independent risk factors for ESBL-UTI.
SponsorNone. This study was approved by the Institutional Review Board of Medical Research Centre, Hamad Medical Corporation (Approval No. MRC-01-20-006).
Languageen
PublisherElsevier
SubjectAntibiotics
ESBL
Extended-spectrum beta-lactamase
Urinary tract infections
TitleEpidemiology of urinary tract infection in adults caused by extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae - a case-control study from Qatar
TypeArticle
Pagination278-286
Volume Number3
dc.accessType Open Access


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