College of Pharmacy: Recent submissions
Now showing items 21-40 of 58
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ANTICANCER EFFECTS OF MODIFIED CITRUS PECTIN AND CURCUMIN IN CHITOSAN NANOPARTICLES ON COLON CANCER
(06-2 , Master Thesis)We aimed to study the influence of stirring effect while modifying citrus pectin (CP), in addition to create a combination of curcumin in chitosan-modified citrus pectin (CCM-NPs) nanoparticles, along with Galectin-3 in ... -
CLINICAL AND ECONOMIC IMPACT OF GENETIC AND NON-GENETIC FACTORS ON INR NORMALIZATION IN PRE-OPERATIVE MANAGEMENT OF WARFARIN PATIENTS
(2021 , Dissertation)The aim of this Ph.D. was to evaluate the periprocedural anticoagulation management of patients receiving warfarin in Qatar clinically and economically. In addition, exploring the clinical and economic impact of genetic ... -
Cost-effectiveness Analysis of Ibuprofen versus Indomethacin or Paracetamol for the Treatment of Patent Ductus Arteriosus in Preterm Neonates
(2021 , Master Thesis)Objective: This thesis sought to evaluate the cost-effectiveness of oral paracetamol and intravenous (IV) indomethacin as alternatives to ibuprofen for patent ductus arteriosus (PDA) in neonates in Hamad Medical Corporation ... -
CLINICAL AND PHARMACOECONOMIC ANALYSES OF CDK4/6 INHIBITORS USE IN STAGE IV BREAST CANCER FEMALES IN THE STATE OF QATAR: A COMPARATIVE RETROSPECTIVE OBSERVATIONAL STUDY WITH COST-EFFECTIVENESS AND COST-UTILITY ANALYSES
(2021 , Master Thesis)Introduction: Cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitors are indicated in the first-line treatment of hormonal receptor positive and HER-2 negative (HR+/HER2- negative) advanced breast cancer. Although phase III ... -
ASSESSMENT OF ADHERENCE, BARRIERS AND STRENGTHS TO ADHERENCE AMONG ADOLESCENTS WITH TYPE 1 DIABETES IN QATAR: PERSPECTIVES OF PATIENTS AND THEIR CAREGIVERS
(2021 , Master Thesis)Background: Metabolic control among adolescents with type 1 diabetes mellitus (T1DM) is generally poor. Non-adherence is one of the contributors to this poor glycemic control, leading to high complication rates. The objective ... -
MOLECULAR FEATURES OF TRIPLE NEGATIVE BREAST CANCER STEM CELLS: A GENE EXPRESSION PROFILING ANALYSIS OF MDA-MB-231 CELLS
(2021 , Master Thesis)Triple negative breast cancer (TNBC) is a chemoresistant subtype of female breast tumors. Chemoresistance is attributed to the presence of long-lived cancer stem cells (CSCs) responsible for therapy failure. This study ... -
MODULATION OF THE MOLECULAR EXPRESSION AND FUNCTION OF BCL-2 FAMILY PROTEINS BY THE ARYL HYDROCARBON RECEPTOR IN BREAST CANCER STEM CELLS OF THE MDA-MB-231
(2021 , Master Thesis)Breast cancer (BC) is a frequently occurring neoplasm in women and is a second major cause of cancer related deaths. Despite the remarkable advancements in the understanding of BC and its treatments, the diseases still ... -
COMMUNITY PHARMACISTS' SELF-PERCEIVED COMPETENCY, AND ENABLERS, AND BARRIERS TOWARDS THE MANAGEMENT OF COMMON MINOR AILMENTS IN QATAR
(2021 , Master Thesis)The study aimed to assess community pharmacists' self-perceived competency, and enablers and barriers towards managing common minor ailments in Qatar, and its predictors. A cross-sectional study, with pretested questionnaires, ... -
A COST-EFFECTIVENESS ANALYSIS FOR HIGH VERSUS LOW DOSE CAFFEINE FOR THE TREATMENT OF APNEA IN NEONATAL INTENSIVE CARE UNIT
(2021 , Master Thesis)Objective: This thesis sought to evaluate the cost effectiveness of high dose (HD) caffeine as alternative therapy over the standard low dose (LD) caffeine for apnea of prematurity (AOP) in neonates, in Hamad Medical ... -
Surface Coating of Carbon Nanofiber by Mesoporous Silica: a Promising Strategy to Reduce its Toxicity during Embryogenesis
(2021 , Master Thesis)Although carbon nanofibers (CNFs) have been implicated in biomedical applications, they are still considered as a potential hazard. Conversely, mesoporous silica nanoparticles are generally considered as a suitable and ... -
Evaluation of the Pharmacovigilance System in Qatar: A Mixed Method Study on Structure Process, And Outcome
(2020 , Master Thesis)Introduction: It is evident that pharmacovigilance (PV) centers are the entities required to ensure medication safety and protect public health from drug related morbidity and mortality. In many developing countries PV ... -
Strengthening the Quality of Clinical Pharmacokinetic Studies: Development and Validation of a Critical Appraisal Tool For Clinical Pharmacokinetic Research
(2020 , Master Thesis)Background: Critical appraisal process is central to the practice of evidence-based medicine that aids in assessing the quality of the published scientific knowledge. To our knowledge, there is no critical appraisal ... -
The Impact of Pamam Dendrimers on Her2-Positive Breast Cancer and the Early Stages of Embryogenesis
(2020 , Master Thesis)Poly (amidoamine) (PAMAM) dendrimers are widely used in drug delivery systems and gene transfection as drug carriers. They also exert several biological effects including modulating gene expression and interfering with ... -
Evaluating Pharmacy Health Literacy and Its Barriers among Patients with Cardiovascular Diseases in Qatar
(2020 , Master Thesis)Background: Patients’ health literacy, which is their capacity to obtain, process, and understand basic health information and services needed to make appropriate health decisions, is a critical determinant of whether ... -
Multi-Criteria Decision Analytic Model for the Comparative Formulary Inclusion of Direct Oral Anticoagulant in Qatar
(2020 , Master Thesis)Aim: The formulary inclusion of direct oral anticoagulant (DOACs) in the government hospital health services in Qatar is not comparative or restricted. Requests to include a DOAC in the formulary are typically accepted ... -
Clinical and Economic Evaluation of Surfactant Use in the Management of Meconium Aspiration Syndrome in the Intensive: Care Setting In Qatar
(2020 , Master Thesis)Background. Surfactant replacement therapy is widely used in the management of the life-threatening condition of Meconium Aspiration Syndrome (MAS), with no clear guidance on its best use. This thesis constitutes two ... -
Sleep Patterns among University Students and Insomnia Management in Primary Care Settings in Qatar: A Two-Phase Investigation
(2020 , Master Thesis)Insomnia is a public health concern that affects approximately a third of adult population worldwide. The aim of this research was to investigate insomnia and its management among university students and primary care ... -
Exploring the Impact and Value of Collaborative Care Model in Diabetes Care at a Primary Healthcare Setting In Qatar
(2020 , Master Thesis)Background: Diabetes mellitus (DM) is one of the top health priorities in Qatar due to its high prevalence and negative health consequences. The current prevalence of DM in Qatar is 15.5%, which is projected to increase ... -
Economic Evaluation of the Cyp2c19 Genotype-Guided Antiplatelet Therapy Compared To Universal Use of Ticagrelor or Clopidogrel in Qatar
(2020 , Master Thesis)Background: Clopidogrel requires activation primarily by cytochrome P450 2C19 (CYP2C19). Patients with CYP2C19 loss-of-function alleles (LOF) are at increased risk of major adverse cardiovascular events. Ticagrelor is ... -
THE ROLE OF P90 RIBOSOMAL S6 KINASE AND AUTOPHAGY IN SUNITINIB AND PONATINIB-INDUCED CARDIOTOXICITY
(2019 , Master Thesis)In recent years, the paradigm cancer management has shifted towards a targeted approach. Among the newly targeted anticancer therapies are ponatinib and sunitinib, small molecules tyrosine kinase inhibitors (TKIs), used ...
