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Development and In Vivo Testing of Smart Nanoparticles for Enhanced Anti-Cancer Activity and Reduced Cardiotoxicity Associated with Tyrosine Kinase Inhibitors

Yalcin, Huseyin; Al-Thani, Hissa; Shurbaji, Samar ( Qatar University Press , 2021 , Poster)

Tyrosine kinase inhibitors (TKIs) are new generation of anti-cancer drugs with very high efficiency against cancer cells. However, TKIs are associated with severe cardiotoxicity limiting their clinical benefits. One TKI ...

Characterization of MXene as a Cancer Photothermal Agent Under Physiological Conditions

Shurbaji, Samar; Manaph, Nimshitha P. Abdul; Ltaief, Samia M.; Al-Shammari, Abeer R.; Elzatahry, Ahmed; ... more authors ... less authors ( Frontiers Media , 2021 , Article)

A growing interest has recently emerged in the use of nanomaterials in medical applications. Nanomaterials, such as MXene, have unique properties due to their 2D ultra-thin structure, which is potentially useful in cancer ...