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Microdeletion in a FAAH pseudogene identified in a patient with high anandamide concentrations and pain insensitivity
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Elsevier Ltd
, 2019 , Article)
The study of rare families with inherited pain insensitivity can identify new human-validated analgesic drug targets. Here, a 66-yr-old female presented with nil requirement for postoperative analgesia after a normally ...
Interleukin-4 and interleukin-13 evoke scratching behaviour in mice
(
Blackwell Publishing Ltd
, 2019 , Article)
Persistent and relapsing itch commonly manifests in inflammatory skin disorders such as atopic dermatitis (AD). AD pathogenesis is driven by interleukin-4 (IL-4) and interleukin-13 (IL-13). Dupilumab, a monoclonal antibody ...
Biomarkers of Targeted Therapy and Immuno-Oncology in Cancers Metastatic to the Breast.
(
Lippincott, Williams & Wilkins
, 2019 , Article)
The breast is a rare site for metastases, and their molecular characteristics have not been studied yet. Intrinsic molecular genetics, cancer characteristics, and breast tissue immune responses in diverse metastases to the ...
Compared to What? Is BMI Associated with Histopathological Changes in Laparoscopic Sleeve Gastrectomy Specimens?
(
Springer New York LLC
, 2019 , Article)
Background: Obesity is a risk for many different cancers. Laparoscopic sleeve gastrectomy (LSG) is common, and benign or pre-malignant histopathology types are reported in the removed gastric specimens. We assessed whether ...
Sorting Out the Myths from the Facts: Commentary on Yasemen Adali et al. (2018) article " The Relationship Between Histopathologic Findings and Body Mass Index in Sleeve Gastrectomy Materials "
(
Springer New York LLC
, 2019 , Article)
[No abstract available]
Rare presentation of primary varicella zoster as fatal fulminant hepatitis in adult on low-dose,short-term steroid: Case report
(
Elsevier Ltd
, 2019 , Article)
Background
Varicella zoster virus presents clinically as primary (chickenpox) or secondary (herpes zoster) infection. Cutaneous and extracutaneous dissemination may occur, usually in immunocompromised patients. VZV ...
Gene expression and miRNAs profiling: Function and regulation in human epidermal growth factor receptor 2 (HER2) - positive breast cancer
(
MDPI AG
, 2019 , Article)
Breast cancer is the second most common cause of cancer-related deaths among women worldwide. It is a heterogeneous disease with four major molecular subtypes. One of the subtypes, human epidermal growth factor receptor 2 ...
Acquisition of invasiveness by breast adenocarcinoma cells engages established hallmarks and novel regulatory mechanisms
(
International Institute of Anticancer Research
, 2019 , Article)
Background/Aim: Proteomics of invasiveness opens a window on the complexity of the metastasis-engaged mechanisms. The extend and types of this complexity require elucidation. Materials and Methods: Proteomics, immuno ...
Assessment of PULP score in predicting 30-day perforated duodenal ulcer morbidity, and comparison of its performance with Boey and ASA, a retrospective study
(
Elsevier Ltd
, 2019 , Article)
Background: /aim: Scores commonly employed to risk stratify perforated peptic ulcer patients include ASA (American Society of Anesthesiologists), Boey and peptic ulcer perforation score (PULP). However, few studies assessed ...
Structure and Rheological Properties of Bovine Aortic Heart Valve and Pericardium Tissue: Implications in Bioprosthetic and Tissue-Engineered Heart Valves
(
Hindawi Limited
, 2019 , Article)
Heart valve (HV) diseases are among the leading causes of cardiac failure and deaths. Of the various HV diseases, damaged HV leaflets are among the primary culprits. In many cases, impaired HV restoration is not always ...