Browsing by Author "Al-Asmakh, Maha"
Now showing items 1-13 of 13
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Application of proteomics for novel drug discovery and risk prediction optimisation in stroke and myocardial infarction: a review of in-human studies.
( Elsevier Ltd , 2024 , Article)The use of proteomics in human studies investigating stroke and myocardial infarction (MI) has been increasing, prompting a review of the literature. This revealed proteinaceous biomarkers of stroke from thrombi, brain ... -
Biochemical and cellular basis of oxidative stress: Implications for disease onset
( Wiley , 2023 , Article Review)Cellular oxidation–reduction (redox) systems, which encompass pro- and antioxidant molecules, are integral components of a plethora of essential cellular processes. Any dysregulation of these systems can cause molecular ... -
The Effects of Gum Acacia on the Composition of the Gut Microbiome and Plasma Levels of Short-Chain Fatty Acids in a Rat Model of Chronic Kidney Disease
( Frontiers Media , 2020 , Article)Chronic kidney disease (CKD) may be fatal for its victims and is an important long-term public health problem. The complicated medical procedures and diet restrictions to which patients with CKD are subjected alter the gut ... -
Hepatic circadian clock oscillators and nuclear receptors integrate microbiome-derived signals
( Nature Publishing Group , 2016 , Article)The liver is a key organ of metabolic homeostasis with functions that oscillate in response to food intake. Although liver and gut microbiome crosstalk has been reported, microbiome-mediated effects on peripheral circadian ... -
Human microbiome and its association with health and diseases
( Wiley , 2016 , Article)Human microbiota are distinct communities of microorganisms that resides at different body niches. Exploration of the human microbiome has become a reality due to the availability of powerful metagenomics and metatranscriptomic ... -
The impact of microbial composition on postprandial glycaemia and lipidaemia: A systematic review of current evidence
( Multidisciplinary Digital Publishing Institute (MDPI) , 2021 , Article)Postprandial hyperglycaemia is associated with increased risk of cardiovascular disease. Recent studies highlight the role of the gut microbiome in influencing postprandial glycaemic (PPG) and lipidaemic (PPL) responses. ... -
Intermittent fasting favorably modulates adipokines and potentially attenuates atherosclerosis
( Elsevier Inc. , 2023 , Article)Adipose tissue is now recognized as an endocrine organ that secretes bioactive molecules called adipokines. These biomolecules regulate key physiological functions, including insulin sensitivity, energy metabolism, appetite ... -
The Interplay Between Diet and the Epigenome in the Pathogenesis of Type-1 Diabetes
( Frontiers , 2021 , Article Review)The autoimmune disease, Type 1 Diabetes Mellitus (T1DM), results in the destruction of pancreatic β-cells, and the International Diabetes Federation reports that its incidence is increasing worldwide. T1DM is a complex ... -
Maternal microbiota regulate glucocorticoids levels and placental development in mice
( bioscientifica , 2015 , Conference)The gut microbiota contributes to postnatal development and maturation by influencing barrier functions of the intestinal wall, the development of the immune system, and the utilisation of nutrients. Recent studies have ... -
Microbiota and the control of blood-tissue barriers
( Taylor & Francis , 2015 , Article)The gastro-intestinal tract is an ecosystem containing trillions of commensal bacteria living in symbiosis with the host. These microbiota modulate a variety of our physiological processes, including production of vitamins, ... -
“Safe” Chitosan Zinc Oxide Nanocomposite Has Minimal Organ-Specific Toxicity on Early Stages of Zebrafish Development
( American Chemical Society , 2019 , Article)Marine biofouling is considered one of the most challenging issues affecting maritime industries worldwide. In this regard, traditional biocides, being used to combat biofouling, have high toxicity toward the aquatic system. ... -
SARS-CoV-2 and immune-microbiome interactions: Lessons from respiratory viral infections
( Elsevier , 2021 , Article)By the beginning of 2020, infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) had rapidly evolved into an emergent worldwide pandemic, an outbreak whose unprecedented consequences highlighted ... -
Use of Germ-Free Animal Models in Microbiota-Related Research
( The Korean Society for Microbiology and Biotechnology , 2015 , Article)The large intestine is a home for trillions of microbiota, which confer many benefits on the host, including production of vitamins, absorption of nutrients, pathogen displacement, and development of the immune system. For ...
