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السجلات المعروضة 81 -- 100 من 1357
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A novel human pain insensitivity disorder caused by a point mutation in ZFHX2
( Oxford University Press , 2018 , Article)Chronic pain is a major global public health issue causing a severe impact on both the quality of life for sufferers and the wider economy. Despite the significant clinical burden, little progress has been made in terms ... -
A History of Drug-Induced Torsades de Pointes Is Associated With T-wave Morphological Abnormalities
( Nature Publishing Group , 2018 , Article)The hypothesis of the study is that Torsades de pointes (TdP) history can be better identified using T-wave morphology compared to Fridericia-corrected QT interval (QTcF) at baseline. ECGs were recorded at baseline and ... -
Current status of tissue engineering in the management of severe hypospadias
( Frontiers Media S.A. , 2018 , Article Review)Hypospadias, characterized by misplacement of the urinary meatus in the lower side of the penis, is a frequent birth defect in male children. Because of the huge variation in the anatomic presentation of hypospadias, no ... -
In vitro effects of hydrogen peroxide on rat uterine contraction before and during pregnancy
( Medicinska Naklada Zagreb , 2018 , Article)Aim To assess the in vitro effect of hydrogen peroxide (H 2 O 2 ) on uterine contractions in pregnant and non-pregnant rats. Methods The study was performed at the Department of Physiology, College of Medicine, King Saud ... -
Attitudes and barriers towards using complementary and alternative medicine among university students in Jordan
( Churchill Livingstone , 2018 , Article)Background: Perceptions towards Complementary and Alternative Medicine (CAM) are highly variable but are improving globally. However, studies conducted in Jordan about CAM are insufficient. This study aims to explore the ... -
Comparison of fosfomycin against fluoroquinolones for transrectal prostate biopsy prophylaxis: an individual patient-data meta-analysis
( Springer Verlag , 2018 , Article Review)Purpose: Rectal culture screening for fluoroquinolone (FQ)-resistant Enterobacteriaceae before transrectal ultrasound guided prostate (TRUSPB) biopsy and targeted antibiotic prophylaxis (TAP) may decrease post-TRUSPB ... -
Digenic inheritance and genetic modifiers
( Blackwell Publishing Ltd , 2018 , Article Review)Digenic inheritance (DI) concerns pathologies with the simplest form of multigenic etiology, implicating more than 1 gene (and perhaps the environment). True DI is when biallelic or even triallelic mutations in 2 distinct ... -
Oxidation–reduction potential and sperm DNA fragmentation, and their associations with sperm morphological anomalies amongst fertile and infertile men
( Arab Association of Urology , 2018 , Article)Objective: To assess seminal oxidation–reduction potential (ORP) and sperm DNA fragmentation (SDF) in male infertility and their relationships with sperm morphology in fertile and infertile men. Patients and methods: ... -
Evolution of 29 Anthropometric, Nutritional, and Cardiometabolic Parameters Among Morbidly Obese Adolescents 2 Years Post Sleeve Gastrectomy
( Springer New York LLC , 2018 , Article)Background: Laparoscopic sleeve gastrectomy (LSG) is a popular treatment for adolescent morbid obesity. Research on LSG outcomes among adolescents assessed a narrow range of anthropometric, nutritional, or cardiometabolic ... -
Chromosomal abnormalities in infertile men with azoospermia and severe oligozoospermia in Qatar and their association with sperm retrieval intracytoplasmic sperm injection outcomes
( Arab Association of Urology , 2018 , Article)Objective: To study the types and incidence of chromosomal abnormalities in infertile men with azoospermia and severe oligozoospermia in Qatar, and to compare the hormonal changes, testicular sperm retrieval rate, and ... -
In honour of Professor Leaf Huang, recipient of the Journal of Drug Targeting's life-time achievement award for 2018
( Taylor and Francis Ltd , 2018 , Article)[No abstract available] -
Characterization and assessment of potential microRNAs involved in phosphate-induced aortic calcification
( Wiley-Liss Inc. , 2018 , Article)Medial artery calcification, a hallmark of type 2 diabetes mellitus and chronic kidney disease (CKD), is known as an independent risk factor for cardiovascular mortality and morbidity. Hyperphosphatemia associated with CKD ... -
Clinical presentation, management, and pathophysiology of neuropathic itch
( Lancet Publishing Group , 2018 , Article Review)Unlike conventional itch, neuropathic itch develops in normal skin from excess peripheral firing or dampened central inhibition of itch pathway neurons. Neuropathic itch is a symptom of the same central and peripheral ... -
The largest reported papillary thyroid carcinoma arising in struma ovarii and metastasis to opposite ovary: Case report and review of literature
( BioMed Central Ltd. , 2018 , Article)Background: Malignant struma ovarii (MSO) is a very rare, germ cell tumor of the ovary, histologically identical to differentiated thyroid cancers. Struma ovarii (SO) is difficult to diagnose on clinical basis or imaging ... -
Association of cardiac myosin-binding protein-C with the ryanodine receptor channel - putative retrograde regulation?
( Company of Biologists Ltd , 2018 , Article)The cardiac muscle ryanodine receptor-Ca2+ release channel (RyR2) constitutes the sarcoplasmic reticulum (SR) Ca2+ efflux mechanism that initiates myocyte contraction, while cardiac myosin-binding protein-C (cMyBP-C; also ... -
Geographical differences in semen characteristics of 13 892 infertile men
( Arab Association of Urology , 2018 , Article)Objective: To assess the relationship between geographical differences and all semen parameters, across 13,892 infertile men of 84 diverse nationalities, recruited at a specialised tertiary hospital that represents the ... -
A comparison between the effectiveness of PBL and LBL on improving problem-solving abilities of medical students using questioning
( Routledge , 2018 , Article)In daily patient-history taking and diagnosis practice, doctors ask questions to gather information from patients and narrow down diagnostic hypotheses. Training medical students to be efficient problem solvers through the ... -
The effectiveness of targeted relative to empiric prophylaxis on infectious complications after transrectal ultrasound-guided prostate biopsy: a meta-analysis
( Springer Verlag , 2018 , Article Review)Purpose: Rectal culture screening for fluoroquinolone (FQ)-resistant Enterobacteriaceae before transrectal ultrasound guided prostate (TRUSPB) biopsy and targeted antibiotic prophylaxis (TAP) may decrease post-TRUSPB ... -
Driver Drowsiness Detection Study using Heart Rate Variability analysis in Virtual Reality Environment
( Hamad bin Khalifa University Press (HBKU Press) , 2018 , Conference Paper)Introduction Mobility and road safety is one of the grand challenges that Qatar is facing during the last decade. There are many ways to enhance the road safety. One way is to characterize the factors contributing to the ... -
Phospholipase C zeta and calcium oscillations at fertilisation: The evidence applications and further questions
( Elsevier Ltd , 2018 , Article)Oocyte activation is a fundamental event at mammalian fertilisation, initiated by a series of characteristic calcium (Ca2+) oscillations in mammals. This characteristic pattern of Ca2+ release is induced in a species-specific ...