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A free terminal ileal perforation as the presenting sign of crohn’s disease in an adolescent female
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University Clinical Hospital Tuzla
, 2020 , Article)
The authors present a rare case of Aa free terminal ileal perforation as the presenting sign of Crohn's disease in an adolescent female.
Comparison of the biomarkers for targeted therapies in primary extra-mammary and mammary Paget's disease.
(
Wiley Open Access
, 2020 , Article)
Primary Extra-mammary Paget's disease (EMPD) is a very rare cutaneous adenocarcinoma affecting anogenital or axillary regions. It is characterized by a prolonged course with recurrences and eventually distant metastatic ...
Apocynin and catalase prevent hypertension and kidney injury in Cyclosporine A-induced nephrotoxicity in rats.
(
Public Library of Science
, 2020 , Article)
Oxidative stress is involved in the pathogenesis of a number of diseases including hypertension and renal failure. There is enhanced expression of nicotinamide adenine dinucleotide (NADPH oxidase) and therefore production ...
Identification of an amino-terminus determinant critical for ryanodine receptor/Ca2+ release channel function.
(
Oxford University Press
, 2020 , Article)
The cardiac ryanodine receptor (RyR2), which mediates intracellular Ca2+ release to trigger cardiomyocyte contraction, participates in development of acquired and inherited arrhythmogenic cardiac disease. This study was ...
The efficacy of colchicine in the management of coronavirus disease 2019: A protocol for systematic review and meta-analysis
(
Lippincott, Williams & Wilkins
, 2020 , Article)
BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS-COV2) infection is a recently emerged viral infection causing predominantly mild upper respiratory symptoms. However, in some instances, it might result in ...
Silencing of Growth Differentiation Factor-15 Promotes Breast Cancer Cell Invasion by Down-regulating Focal Adhesion Genes.
(
International Institute of Anticancer Research
, 2020 , Article)
As metastasis accounts for most breast cancer (BC)-related deaths, identifying key players becomes research priority. Growth differentiation factor-15 (GDF15), a member of the transforming growth factor-β superfamily, is ...
EMT Factors and Metabolic Pathways in Cancer.
(
Frontiers Media
, 2020 , Article)
The epithelial-mesenchymal transition (EMT) represents a biological program during which epithelial cells lose their cell identity and acquire a mesenchymal phenotype. EMT is normally observed during organismal development, ...
Signatures of co-deregulated genes and their transcriptional regulators in colorectal cancer.
(
Nature Research
, 2020 , Article)
The deregulated genes in colorectal cancer (CRC) vary significantly across different studies. Thus, a systems biology approach is needed to identify the co-deregulated genes (co-DEGs), explore their molecular networks, and ...
Performance evaluation of five ELISA kits for detecting anti-SARS-COV-2 IgG antibodies
(
Elsevier
, 2020 , Article)
ObjectivesTo evaluate and compare the performances of five commercial ELISA assays (EDI, AnshLabs, Dia.Pro, NovaTec, and Lionex) for detecting anti-SARS-CoV-2 IgG. Methods70 negative control samples (collected before the ...
Cutaneous Aβ-Non-nociceptive, but Not C-Nociceptive, Dorsal Root Ganglion Neurons Exhibit Spontaneous Activity in the Streptozotocin Rat Model of Painful Diabetic Neuropathy .
(
Frontiers Media
, 2020 , Article)
Diabetic peripheral neuropathic pain (DPNP) is the most devastating complication of diabetes mellitus. Unfortunately, successful therapy for DPNP remains a challenge because its pathogenesis is still elusive. However, DPNP ...