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ILK silencing inhibits migration and invasion of more invasive glioblastoma cells by downregulating ROCK1 and Fascin-1.
(
Springer
, 2020 , Article)
Glioblastoma multiforme (GBM) is the most aggressive type of brain tumor and it is associated with poor survival. Integrin-linked kinase (ILK) is a serine/threonine protein pseudo-kinase that binds to the cytoplasmic domains ...
Inter-rater reliability, intra-rater reliability and internal consistency of the Brisbane Evidence-Based Language Test.
(
Taylor & Francis
, 2020 , Article)
To examine the inter-rater reliability, intra-rater reliability, internal consistency and practice effects associated with a new test, the Brisbane Evidence-Based Language Test. Reliability estimates were obtained in a ...
Updated lower limb stature estimation equations for a South African population group
(
Academy of Science of South Africa
, 2020 , Article)
© 2020. The Author(s). Published under a Creative Commons Attribution Licence. One of the main steps in the identification of an unknown person, from their skeletal remains, is the estimation of stature. Measurements of ...
Phospholipase C zeta profiles are indicative of optimal sperm parameters and fertilisation success in patients undergoing fertility treatment.
(
wiley
, 2020 , Article)
Oocyte activation is driven by intracellular calcium (Ca ) oscillations induced by sperm-specific PLCζ, abrogation of which causes oocyte activation deficiency in humans. Clinical PLCζ investigations have been limited to ...
Mutual inter-regulation between iNOS and TGF-β1: Possible molecular and cellular mechanisms of iNOS in wound healing.
(
Elsevier
, 2020 , Article)
Abnormal wound healing with excessive scarring is a major health problem with socioeconomic and psychological impacts. In human, chronic wounds and scarring are associated with upregulation of the inducible nitric oxide ...
MXene Nanosheets May Induce Toxic Effect on the Early Stage of Embryogenesis.
(
American Scientific Publishers
, 2020 , Article)
MXene (Ti₃C₂T), as a novel 2D material, has produced a great interest due to its promising properties in biomedical applications, nevertheless, there is a lack of studies dedicated to investigate the possible toxic effect ...
Human papillomavirus E7 binds Oct4 and regulates its activity in HPV-associated cervical cancers.
(
Public Library of Science
, 2020 , Article)
Octamer binding transcription factor-4 (Oct4), is highly expressed in stem cells and has indispensable roles in pluripotency and cellular reprogramming. In contrast to other factors used for cellular reprogramming, a role ...
The Non-Coding RNA and Its Role in Tumor Therapy-Induced Resistance.
(
MDPI
, 2020 , Article)
The growth arrest-specific transcript 5 () is a >200-nt lncRNA molecule that regulates several cellular functions, including proliferation, apoptosis, invasion and metastasis, across different types of human cancers. Here, ...
68 Ga-PSMA PET/CT tumour intensity pre-operatively predicts adverse pathological outcomes and progression-free survival in localised prostate cancer
(
Springer
, 2020 , Article)
© 2020, Springer-Verlag GmbH Germany, part of Springer Nature. Purpose: Prostate-specific membrane antigen (PSMA) positron emission tomography (PSMA-PET) improves prostate cancer staging. Intraprostatic PSMA intensity may ...
Global incidence of caesarean deliveries on maternal request: a systematic review and meta-regression.
(
Wiley
, 2020 , Article)
Caesarean delivery on maternal request (CDMR) is considered a significant contributor to the unprecedented increase in caesarean deliveries (CDs) for nonclinical reasons. Current literature lacks a reliable assessment of ...