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Now showing items 131-140 of 272
A review of breast cancer pathology reports in Nigeria
(
ecancer Global Foundation
, 2021 , Article Review)
Background: Diagnosis and treatment of cancer rely heavily on imaging, histopathology and molecular information. Incomplete or missing tumour information can hinder the delivery of high-quality care in oncology practice, ...
Towards a better understanding of self-management interventions in type 2 diabetes: A meta-regression analysis
(
Elsevier Ltd
, 2021 , Article)
Aims: Attributes that operationally conceptualize diabetes self-management education (DSME) interventions have never been studied previously to assess their impact on relevant outcomes of interest in people with type 2 ...
Reply to: Let us not rush back to odds ratios in meta-analysis
(
Elsevier Inc.
, 2021 , Article)
[No abstract available]
An evidence base for school health policy during the covid-19 pandemic
(
Paris Scholar Publishing
, 2021 , Article)
Objective: Children represent a small fraction of confirmed COVID-19 cases, with a low case fatality rate (CFR). In this paper, we lay out an evidence-based policy for reopening schools. Methods: We gathered age-specific ...
Increased de novo DNA methylation enzymes in sperm of individuals with varicocele
(
pmc
, 2021 , Article)
Objective: Chronic genital heat-stress associated with varicocele leads to DNA hypo-methylation of spermatozoa. The objective of this study was comparing level of DNA methyl-transferases (DNMTs) in sperm of men suffering ...
Advancing male age differentially alters levels and localization patterns of PLCzeta in sperm and testes from different mouse strains
(
Medknow Publications
, 2021 , Article)
Sperm-specific phospholipase C zeta (PLC) initiates intracellular calcium (Ca2+) transients which drive a series of concurrent events collectively termed oocyte activation. Numerous investigations have linked abrogation ...
Mesoporous silica coated carbon nanofibers reduce embryotoxicity via ERK and JNK pathways
(
Elsevier Ltd
, 2021 , Article)
Carbon nanofibers (CNFs) have been implicated in biomedical applications, yet, they are still considered as a potential hazard. Conversely, mesoporous silica is a biocompatible compound that has been used in various ...
The Role of Epidermal Growth Factor Receptor Family of Receptor Tyrosine Kinases in Mediating Diabetes-Induced Cardiovascular Complications
(
Frontiers Media S.A.
, 2021 , Article)
Diabetes mellitus is a major debilitating disease whose global incidence is progressively increasing with currently over 463 million adult sufferers and this figure will likely reach over 700 million by the year 2045. It ...
Immunogenicity after pre- and post-exposure rabies vaccination: A systematic review and dose-response meta-analysis
(
Elsevier
, 2021 , Article)
There are a myriad of vaccine schedules for rabies pre- (PrEP) and post-exposure prophylaxis (PEP) that differ in the number and timedoses, number of visits, length of schedule, and route of administration. The objective ...
F-box proteins in cancer stemness: An emerging prognostic and therapeutic target
(
Elsevier
, 2021 , Article)
Cancer is a complex heterogenic disease with significant therapeutic challenges. The presence of cancer stem cells (CSCs) in cancer tissue orchestrates tumor growth, progression, and metastasis, the tumor heterogeneity, ...