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Now showing items 91-100 of 249
Preliminary investigation of elevated collagen and blood-clotting markers as potential noninvasive biomarkers for small cell lung cancer
(
John Wiley and Sons Inc
, 2023 , Article)
Background: Small cell lung cancer (SCLC) is highly aggressive with limited therapeutic options and a poor prognosis. Moreover, noninvasive biomarker tools for detecting disease and monitoring treatment response are lacking. ...
Shrinking the battlefield in cancer therapy: Nanotechnology against cancer stem cells
(
Elsevier
, 2023 , Article)
Cancer remains one of the leading causes of mortality worldwide, presenting a significant healthcare challenge owing to the limited efficacy of current treatments. The application of nanotechnology in cancer treatment ...
Adverse childhood experiences, the risk of pregnancy complications and adverse pregnancy outcomes: a systematic review and meta-analysis
(
BMJ Publishing Group
, 2023 , Article)
Background Adverse childhood experiences (ACEs) have a profound negative impact on health. However, the strength of the association between ACEs and pregnancy complications and adverse pregnancy outcomes is not well ...
Association of Blood Levels of Vitamin D and Its Binding Protein with Clinical Phenotypes of Multiple Sclerosis.
(
MDPI
, 2023 , Article)
Low vitamin D levels may synergize with changing levels of the vitamin D binding protein (DBP) to precipitate in the development and clinical progression of multiple sclerosis (MS). In this study, this hypothesis was ...
In vitro evaluation of Neosetophomone B inducing apoptosis in cutaneous T cell lymphoma by targeting the FOXM1 signaling pathway
(
Elsevier
, 2023 , Article)
Background: Cutaneous T cell lymphoma (CTCL) is a T cell-derived non-Hodgkin lymphoma primarily affecting the skin, with treatment posing a significant challenge and low survival rates. Objective: In this study, we ...
Immunotherapy and immunoevasion of colorectal cancer
(
Elsevier
, 2023 , Article Review)
The tremendous success of immunotherapy in clinical trials has led to its establishment as a new pillar of cancer therapy. However, little clinical efficacy has been achieved in microsatellite stable colorectal cancer ...
Bias assessment: mQ or RoB?
(
Lippincott, Williams & Wilkins
, 2023 , Other)
In a recent paper in the journal, Stone et al. propose that JBI adopt the term risk of bias (RoB) wherever critical appraisal, study validity, method- ological quality (mQ), or methodological limitations are used. The ...
BIO-CXRNET: a robust multimodal stacking machine learning technique for mortality risk prediction of COVID-19 patients using chest X-ray images and clinical data
(
Springer Science and Business Media Deutschland GmbH
, 2023 , Article)
Nowadays, quick, and accurate diagnosis of COVID-19 is a pressing need. This study presents a multimodal system to meet this need. The presented system employs a machine learning module that learns the required knowledge ...
MicroRNA-mediated regulation of LDL receptor: biological and pharmacological implications.
(
Europe PM
, 2023 , Article)
One of the main causes of atherosclerosis is a disruption in cellular cholesterol hemostasis. The low-density lipoprotein receptor (LDLR) is an important factor in maintaining cholesterol homeostasis by the receptor-mediated ...
Response to Mindel C. Sheps: Counted, Dead or Alive
(
Lippincott Williams and Wilkins
, 2023 , Other)
It is true that when decision-making in medicine proceeds (e.g., drug A to prevent outcome Y), clinicians make use of research results that are reported in terms of estimated probabilities. Thus, Pr [Ya = 1 = 1] is the ...