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Clinical assessment and risk stratification for prehospital use of methoxyflurane versus standard analgesia in adult patients with trauma pain
(
PMC
, 2023 , Article)
Oligoanalgesia, the undertreatment of trauma-related pain using standard analgesics in prehospital and emergency departments, has been extensively documented as one of the major challenges affecting the effective treatment ...
Comprehensive genomic profiling of a metastatic small cell lung carcinoma with a complete and long-term response to atezolizumab: A case report
(
Elsevier
, 2023 , Article)
Small cell lung cancer (SCLC) is a highly aggressive malignancy with a poor outcome. We present the case of a 57-year-old male patient with extensive-stage (ES-SCLC) treated with chemotherapy and atezolizumab. A complete ...
Development of an evidence-based model for predicting patient, provider, and appointment factors that influence no-shows in a rural healthcare system
(2023 , Article)
Background: No-show appointments pose a significant challenge for healthcare providers, particularly in rural areas. In this study, we developed an evidence-based predictive model for patient no-shows at the Marshfield ...
Effect of Bariatric Surgery on Serum Amyloid A Protein: a Systematic Review and Meta-analysis
(
springer link
, 2023 , Article)
Background: Obesity is a chronic inflammatory condition and this meta-analysis evaluated the impact of bariatric surgery on SAA. Methods: Studies included all types of bariatric surgery where SAA was measured before and ...
IP3 receptors: An "elementary" journey from structure to signals
(
Elsevier
, 2023 , Article)
Inositol 1,4,5-trisphosphate receptors (IP3Rs) are large tetrameric channels which sit mostly in the membrane of the endoplasmic reticulum (ER) and mediate Ca2+ release from intracellular stores in response to extracellular ...
RamanNet: a generalized neural network architecture for Raman spectrum analysis
(
Springer Science and Business Media Deutschland GmbH
, 2023 , Article)
Raman spectroscopy provides a vibrational profile of the molecules and thus can be used to uniquely identify different kinds of materials. This sort of molecule fingerprinting has thus led to the widespread application of ...
Thermogenic Modulation of Adipose Depots: A Perspective on Possible Therapeutic Intervention with Early Cardiorenal Complications of Metabolic Impairment
(
American Society for Pharmacology and Experimental Therapy (ASPET)
, 2023 , Article)
Cardiovascular complications of diabetes and obesity remain a major cause for morbidity and mortality worldwide. Despite significant advances in the pharmacotherapy of metabolic disease, the available approaches do not ...
The attitude and knowledge of pediatricians and family physicians toward COVID-19 vaccination in children: A cross-sectional study
(
Taylor and Francis Ltd.
, 2023 , Article)
COVID-19 vaccines to children are expected to reduce the transmission of the disease to high-risk groups and achieve herd immunity in younger populations. A positive attitude toward COVID-19 vaccination in children among ...
An Adjuvanted Inactivated SARS-CoV-2 Microparticulate Vaccine Delivered Using Microneedles Induces a Robust Immune Response in Vaccinated Mice
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2023 , Article)
SARS-CoV-2, the causal agent of COVID-19, is a contagious respiratory virus that frequently mutates, giving rise to variant strains and leading to reduced vaccine efficacy against the variants. Frequent vaccination against ...
Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals over 10 months
(
Elsevier
, 2023 , Article)
BackgroundEvidence on the effectiveness of vaccination-induced immunity compared to SARS-CoV-2 natural immunity is warranted to inform vaccination recommendations. AimIn this study, we aimed to conduct a comparative ...