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Duration of symptoms is the only predictor of testicular salvage following testicular torsion in children: A case-control study
(
Elsevier
, 2020 , Article)
ObjectiveTesticular torsion (TT) is an emergency requiring a prompt diagnosis and surgery to avoid irreversible changes and a complete loss of testis. The present study aimed to identify potential factors that may be predict ...
Pharmacologic inhibition of hypoxia-inducible factor (HIF)-hydroxylases ameliorates allergic contact dermatitis
(
Blackwell Publishing Ltd
, 2019 , Article)
Background
When an immune cell migrates from the bloodstream to a site of chronic inflammation, it experiences a profound decrease in microenvironmental oxygen levels leading to a state of cellular hypoxia. The hypoxia‐inducible ...
The Odds Ratio is "portable" across baseline risk but not the Relative Risk: Time to do away with the log link in binomial regression
(
Elsevier Inc.
, 2022 , Article)
Objectives: In a recent paper we suggest that the relative risk (RR) be replaced with the odds ratio (OR) as the effect measure of choice in clinical epidemiology. In response, Chu, and colleagues raise several points that ...
Impaired Binding to Junctophilin-2 and Nanostructural Alteration in CPVT Mutation
(
American Heart Association
, 2021 , Article)
RATIONALE: Catecholaminergic polymorphic ventricular tachycardia is a rare disease, manifested by syncope or sudden death
in children or young adults under stress conditions. Mutations in the Ca2+ release channel/type 2 ...
Stature estimation from the femur and tibia in Black South African sub-adults
(
Elsevier
, 2017 , Article)
Stature estimation can play a role in the positive identification of unknown individuals and as such it is routinely assessed during the examination of adult remains. Unfortunately, this is not a standard procedure when ...
Phospholipase C zeta profiles are indicative of optimal sperm parameters and fertilisation success in patients undergoing fertility treatment.
(
wiley
, 2020 , Article)
Oocyte activation is driven by intracellular calcium (Ca ) oscillations induced by sperm-specific PLCζ, abrogation of which causes oocyte activation deficiency in humans. Clinical PLCζ investigations have been limited to ...
Association Between Metabolic Syndrome and Decline in Cognitive Function: A Cross-Sectional Study
(
Dave Medical Press Limited,
, 2023 , Article)
Aim: We investigated whether metabolic syndrome (MetS) is associated with a decline in cognitive function in a cohort of middle-aged and elderly individuals without known cognitive dysfunction diseases in Qatar. Methods: ...
Nanotoxicology of dendrimers in the mammalian heart: Ex vivo and in vivo administration of g6 pamam nanoparticles impairs recovery of cardiac function following ischemia-reperfusion injury
(
Dove Medical Press Ltd.
, 2020 , Article)
Aim: The effects of polyamidoamine (PAMAM) dendrimers on the mammalian heart are not completely understood. In this study, we have investigated the effects of a sixth-generation cationic dendrimer (G6 PAMAM) on cardiac ...
Stratification by quality induced selection bias in a meta-analysis of clinical trials.
(
Elsevier
, 2018 , Article)
The inconsistency demonstrated across strata when using different scales has been attributed to quality scores and stratification continues to be done using risk of bias domain judgments. This study examines if restricting ...
In honour of Professor Patrick Couvreur, recipient of the Journal Of Drug Targeting?s Lifetime Achievement Award For 2019
(
Taylor and Francis Ltd
, 2019 , Article)
[No abstract available]