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PD-L1 testing by immunohistochemistry in Immuno-Oncology.
(
Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina
, 2022 , Article Review)
Immunotherapy, based on immune checkpoint inhibitors targeting the Programmed cell death ligand 1 (PD-L1) and/or Programmed Death Receptor 1 (PD-1), has substantially improved the outcomes of patients with various cancers. ...
A Giant Polypoid Gastric Heterotopia of the Ileum as a Cause of Intussusception in an Adolescent.
(
Department of Medical Sciences, Academy of Sciences and Arts of Bosnia and Herzegovina, Sarajevo, Bosnia and Herzegovina
, 2022 , Article)
Histopathological examination confirmed a well-demarcated polyp, lined by a foveolar-type epithelium, with all the elements found in the gastric mucosa, and a well-developed gastric gland. No dysplasia or malignancy was ...
Role and Significance of c-KIT Receptor Tyrosine Kinase in Cancer: A Review.
(
Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina
, 2022 , Article Review)
c-kit is a classical proto-oncogene that encodes a receptor tyrosine kinase (RTK) that responds to stem cell factor (SCF). C-KIT signaling is a critical regulator of cell proliferation, survival, and migration and is ...
Comparison of demographic and clinical characteristics in distinguishing testicular torsion from torsion of the appendix testis: A single-center retrospective study
(
Elsevier
, 2022 , Article)
Testicular torsion (TT) is an emergency requiring a prompt diagnosis and surgery to avoid irreversible changes and a complete loss of testis. The present study aimed to identify potential factors that may predict a testicular ...
Successful minimally invasive management of nonvascular grade IV blunt renal trauma with complete transection in a 7-year-old girl
(
Elsevier
, 2022 , Article)
Non-operative treatment of high-grade renal trauma in hemodynamically stable children is gaining increasing acceptance nowadays. However, the management of isolated grade IV injuries, particularly those with complete renal ...
Tumor-Type Agnostic, Targeted Therapies: BRAF Inhibitors Join the Group
(
Academy of Sciences and Arts of Bosnia and Herzegovina
, 2022 , Article)
In the present review, we briefly discuss the breakthrough advances in precision medicine using a tumor-agnostic approach and focus on BRAF treatment modalities, the mechanisms of resistance and the diagnostic approach in ...
Bilateral Morgagni hernia in a two-month-old infant with a history of umbilical cord hernia status-post repair in neonatal period
(
Elsevier
, 2022 , Other)
Morgagni hernias (MH) are a rare form of congenital diaphragmatic hernia (CDH) characterized by herniation of abdominal contents into the thoracic cavity through a retrosternal diaphragmatic defect. MH constitutes <5% of ...
Alpha-methylacyl-CoA Racemase (AMACR) Protein is Upregulated in Early Proliferative Lesions of the Breast Irrespective of Apocrine Differentiation
(
Elsevier
, 2022 , Other)
Alpha-methylacyl-CoA racemase (AMACR/P504S) is a mitochondrial and peroxisomal enzyme involved in the branched-chain fatty acid and bile acid metabolism. AMACR is a useful diagnostic biomarker for prostate carcinomas and ...
An infant with ankyloblepharon filiforme adnatum associated with a cleft lip and palate: A case report
(
Elsevier
, 2022 , Other)
Ankyloblepharon filiform adnatum (AFA) is a rare but potentially ambylogenic congenital anomaly characterized by a partial or complete fusion of the eyelid margins.1 Although AFA has been reported as an isolated finding, ...
Epidemiologic and clinical characteristics of selected congenital anomalies at the largest Bosnian pediatric surgery tertiary center
(
Lippincott, Williams & Wilkins
, 2022 , Article)
Congenital anomalies (CA) are any abnormality present at birth, either structural or functional, that may potentially affect an infant's health, development, and/or survival. There is a paucity of studies on clinical ...