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Novel targetable biomarkers in clear cell carcinoma of the breast uncovered by molecular profiling: A study of nine cases.
(
Wiley
, 2020 , Article)
We profiled nine pure clear cell carcinomas of the breast using massively parallel DNA and RNA sequencing (NGS), in situ hybridization (ISH), and immunohistochemistry (IHC). All cases were primary mammary clear cell ...
Laparoscopic Extirpation of Adrenal Gland Ganglioneuroma Incidentally Diagnosed During Evaluation for Patchy Alopecia Areata in an Adolescent Boy
(
Karger
, 2019 , Article)
We present a 17-year-old boy with an incidentally diagnosed left adrenal ganglioneuroma (GN) during the diagnostic work up of alopecia areata (AA). Clinical Presentation and Intervention Laboratory investigations revealed ...
The co-presence of high-risk human papillomaviruses and Epstein-Barr virus is linked with tumor grade and stage in Qatari women with breast cancer.
(
Taylor and Francis
, 2020 , Article)
High-risk human papillomaviruses (HPV) can be present and cooperate with Epstein-Barr virus (EBV) to promote the onset and/or progression of various cancers including cervical, breast, head and neck as well as colorectal. ...
2020 consensus guideline for optimal approach to the diagnosis and treatment of HER2-positive breast cancer in Bosnia and Herzegovina.
(
Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina
, 2020 , Article)
The HERe2cure project, which involved a group of breast cancer experts, members of multidisciplinary tumor boards from healthcare institutions in Bosnia and Herzegovina, was initiated with the aim of defining an optimal ...
E-Cigarette Liquid Provokes Significant Embryotoxicity and Inhibits Angiogenesis.
(
MDPI
, 2020 , Article)
E-cigarette smoking (ECS) is a new method of tobacco smoking that is gaining popularity as it is thought to be a "healthy method" of tobacco consumption. The adverse outcomes of ECS on the respiratory and cardiovascular ...
Human Papillomaviruses and Epstein-Barr Virus Interactions in Colorectal Cancer: A Brief Review.
(
MDPI
, 2020 , Article)
Human papillomaviruses (HPVs) and the Epstein-Barr virus (EBV) are the most common oncoviruses, contributing to approximately 10%-15% of all malignancies. Oncoproteins of high-risk HPVs (E5 and E6/E7), as well as EBV (LMP1, ...
High-Risk Human Papillomaviruses and Epstein-Barr Virus in Colorectal Cancer and Their Association with Clinicopathological Status.
(
MDPI
, 2020 , Article)
Colorectal cancer (CRC) is a common malignancy with a high mortality rate worldwide. It is a complex, multifactorial disease that is strongly impacted by both hereditary and environmental factors. The role of microbes ...
Biomarkers of Targeted Therapy and Immuno-Oncology in Cancers Metastatic to the Breast.
(
Lippincott, Williams & Wilkins
, 2019 , Article)
The breast is a rare site for metastases, and their molecular characteristics have not been studied yet. Intrinsic molecular genetics, cancer characteristics, and breast tissue immune responses in diverse metastases to the ...
Breast Cancer During Pregnancy: A Marked Propensity to Triple-Negative Phenotype.
(
Frontiers Media
, 2020 , Article)
Breast and cervical cancers comprise 50% of all cancers during pregnancy. In particular, gestational breast cancer is considered one of the most aggressive types of cancers, which is a rare but fatal disease. However, the ...
Circulating miRNAs in HER2-Positive and Triple Negative Breast Cancers: Potential Biomarkers and Therapeutic Targets.
(
MDPI
, 2020 , Article)
Breast cancer is one of the most prevalent diseases among women worldwide and is highly associated with cancer-related mortality. Of the four major molecular subtypes, HER2-positive and triple-negative breast cancer (TNBC) ...