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Comparison of the biomarkers for targeted therapies in primary extra-mammary and mammary Paget's disease.
(
Wiley Open Access
, 2020 , Article)
Primary Extra-mammary Paget's disease (EMPD) is a very rare cutaneous adenocarcinoma affecting anogenital or axillary regions. It is characterized by a prolonged course with recurrences and eventually distant metastatic ...
Potential Novel Therapy Targets in Neuroendocrine Carcinomas of the Breast.
(
Elsevier
, 2018 , Article)
Neuroendocrine carcinoma (NEC) of the breast is a rare, special type of breast cancer, reportedly constituting 2% to 5% of all breast cancers. Although breast NEC does not have a specific targeted therapy, several new ...
Novel targetable biomarkers in clear cell carcinoma of the breast uncovered by molecular profiling: A study of nine cases.
(
Wiley
, 2020 , Article)
We profiled nine pure clear cell carcinomas of the breast using massively parallel DNA and RNA sequencing (NGS), in situ hybridization (ISH), and immunohistochemistry (IHC). All cases were primary mammary clear cell ...
The Role of Pathology in the Era of Personalized (Precision) Medicine: A Brief Review.
(
NLM (Medline)
, 2021 , Article)
This review provides a brief overview of the state-of-the-art molecular pathology approaches emphasizing the increasingly important pathology role in clinical precision cancer medicine. Recent advances in molecular biology ...
Teucrium Polium Plant Extract Provokes Substantial Cytotoxicity at the Early Stage of Embryonic Development.
(
Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina
, 2019 , Article)
The aim of this study is to explore the outcome of Teucrium polium (TP) medicinal plant consumption on the early stage of fetal development. We used the chicken embryo at 3 days of incubation as a model to evaluate the ...
The correlation between ureteric orifice morphology and primary vesicoureteral reflux grade and the impact on the effectiveness of endoscopic reflux correction
(
Elsevier
, 2023 , Article)
IntroductionEarly diagnosis and treatment of primary vesicoureteral reflux (VUR) are essential for preserving renal function. ObjectivesThe study explored whether preoperative cystoscopic grading of refluxing ureteric ...
The utility of a deep learning-based approach in Her-2/neu assessment in breast cancer
(
Elsevier
, 2023 , Article)
IntroductionHER-2/neu is a protein present on the surface of specific cancer cells and has been linked to the development and progression of certain cancer types. It is present in 15 to 20% of breast cancers and is clinically ...
Water-Pipe Smoking Exposure Deregulates a Set of Genes Associated with Human Head and Neck Cancer Development and Prognosis.
(
MDPI
, 2020 , Article)
Water-pipe smoking (WPS) is becoming the most popular form of tobacco use among the youth, especially in the Middle East, replacing cigarettes rapidly and becoming a major risk of tobacco addiction worldwide. Smoke from ...
Clinical course and short-term outcome of postsplenectomy reactive thrombocytosis in children without myeloproliferative disorders: A single institutional experience from a developing country.
(
Public Library of Science
, 2020 , Article)
To evaluate the clinical outcome and complications in the pediatric population who had splenectomy at our institution, emphasizing the incidence of postplenectomy reactive thrombocytosis (RT) and its clinical significance ...
SARS-CoV-2 Infection and Smoking: What is the association? A brief review
(
Elsevier
, 2021 , Article)
Susceptibility to severe illness from COVID-19 is anticipated to be associated with cigarette smoking as it aggravates the risk of cardiovascular and respiratory illness, including infections. This is particularly important ...