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Unveiling a Biomarker Signature of Meningioma: the Need for a Panel of Genomic, Epigenetic, Proteomic, and RNA Biomarkers to Advance Diagnosis and Prognosis
(
MDPI
, 2023 , Unpublished Work)
Meningiomas are the most prevalent primary intracranial tumors. The majority are benign but can undergo dedifferentiation in grades classified from I to III. Meningiomas tremendous variability in tumor behavior and slow ...
Sailing the boat together: Co-creation of a model for learning during transition
(
Taylor and Francis Ltd.
, 2023 , Article)
Purpose
Medical students’ transition to postgraduate training, given the complexity of new roles and responsibilities, requires the engagement of all involved stakeholders. This study aims to co-create a transition ...
Adverse childhood experiences, the risk of pregnancy complications and adverse pregnancy outcomes: a systematic review and meta-analysis
(
BMJ Publishing Group
, 2023 , Article)
Background Adverse childhood experiences (ACEs) have a profound negative impact on health. However, the strength of the association between ACEs and pregnancy complications and adverse pregnancy outcomes is not well ...
Association of Blood Levels of Vitamin D and Its Binding Protein with Clinical Phenotypes of Multiple Sclerosis.
(
MDPI
, 2023 , Article)
Low vitamin D levels may synergize with changing levels of the vitamin D binding protein (DBP) to precipitate in the development and clinical progression of multiple sclerosis (MS). In this study, this hypothesis was ...
Data extraction error in pharmaceutical versus non-pharmaceutical interventions for evidence synthesis: Study protocol for a crossover trial
(
Elsevier
, 2023 , Article)
BackgroundData extraction is the foundation for research synthesis evidence, while data extraction errors frequently occur in the literature. An interesting phenomenon was observed that data extraction error tend to be ...
Bias assessment: mQ or RoB?
(
Lippincott, Williams & Wilkins
, 2023 , Article)
In a recent paper in the journal, Stone et al. propose that JBI adopt the term risk of bias (RoB) wherever critical appraisal, study validity, method- ological quality (mQ), or methodological limitations are used. The ...
The Impact of SARS-CoV-2 Infection in Unvaccinated Multiple Sclerosis Patients on Disease-Modifying Therapies
(
Karger Publishers
, 2023 , Article)
Objective: Disease-modifying therapies (DMTs) in multiple sclerosis (MS) may affect the course and outcome of COVID-19, but withholding them could permit disease activity. This study aimed to understand the course of ...
Response to Mindel C. Sheps: Counted, Dead or Alive
(
Lippincott Williams and Wilkins
, 2023 , Article)
It is true that when decision-making in medicine proceeds (e.g., drug A to prevent outcome Y), clinicians make use of research results that are reported in terms of estimated probabilities. Thus, Pr [Ya = 1 = 1] is the ...
Clinical Phenotypes of PCOS: a Cross-Sectional Study
(
Springer
, 2023 , Article)
This cross-sectional study examines the Doi-Alshoumer PCOS clinical phenotype classification in relation to measured clinical and biochemical characteristics of women with polycystic ovary syndrome (PCOS). Two cohorts of ...
Prevalence and global trends of polypharmacy in patients with chronic liver disease: A systematic review and meta-analysis
(
Wolters Kluwer Health
, 2023 , Article)
Background: Despite its central role in drug metabolism, the exact prevalence estimates and factors affecting global trends of polypharmacy in patients with chronic liver disease (CLD) have remained unexamined. The aim of ...