The host-adapted human pathogen Neisseria gonorrhoeae is the causative agent of sexually transmitted infection gonorrhea. The increased emergence of gonorrhea infections worldwide, associated with the surging resistance ...

Oral cancer is a common neoplasm in both male and female worldwide; the incidence and mortality of this cancer have increased over the past decades. Cancer metastasis is a major cause of morbidity and mortality in oral ...

Traumatic brain injury (TBI) is one of the key causes of deaths and disabilities worldwide. TBI progresses in two phases. The primary phase of injury is the direct result of the physical damage caused by the external force ...

Alzheimer’s disease (AD) is a debilitating neurodegenerative disease with devastating outcomes to patients and exhaustive burdens to healthcare systems. Alzheimer’s disease has always been the focus of extensive research ...

DNA damage can alter nucleotide sequences and lead to expression of dysfunctional proteins that impact normal cellular physiology. Sources of DNA damage can be endogenous or exogenous and include reactive oxygen species ...

With the evolution of different challenging diseases, there is an urgent need of vaccine development against them to save millions of lives around the world. Particlulate delivery system plays an important role by acting ...

Autism is a group of early onsets, diverse, lifelong, neurodevelopmental conditions that affect social interaction, verbal and non-verbal communications as well as behavior. It is a multifactorial condition, which results ...

The Raf kinase inhibitory protein (RKIP) is an inhibitor of the RAF/MEK/ERK and NF-κB signaling pathways, through which it regulates several key processes of the cell's physiology, such as its proliferation, motility and ...

Worldwide use of illicit drugs is increasing, and substance use disorders (SUDs) have become a significant mental health problem in the West. Although the majority of young people do not use illicit drugs and of those who ...

Patterns of normal sleep are considered, including the circadian cycle, which is considered the body's internal clock, REM, and NREM sleep. Sleep disorders are a prevalent problem in the pediatric population, affecting ...