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The role of protein tyrosine phosphatase (PTP)-1B in cardiovascular disease and its interplay with insulin resistance
(
MDPI AG
, 2019 , Article Review)
Endothelial dysfunction is a key feature of cardiovascular disorders associated with obesity and diabetes. Several studies identified protein tyrosine phosphatase (PTP)-1B, a member of the PTP superfamily, as a major ...
Advances in Cardiovascular Biomarker Discovery.
(
MDPI
, 2020 , Article Review)
Cardiovascular diseases are the leading causes of mortality worldwide. Among them, hypertension and its pathological complications pose a major risk for the development of other cardiovascular diseases, including heart ...
Targeted immunotherapy with a checkpoint inhibitor in combination with chemotherapy: A new clinical paradigm in the treatment of triple-negative breast cancer.
(
Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina
, 2019 , Article Review)
The treatment of several solid and hematologic malignancies with immune checkpoint inhibitors (against PD-1/PD-L1) has dramatically changed the cancer treatment paradigm. However, no checkpoint inhibitors were previously ...
Comparative effectiveness of malaria prevention measures: a systematic review and network meta-analysis.
(
BMC
, 2018 , Article Review)
Malaria causes significant morbidity and mortality worldwide. There are several preventive measures that are currently employed, including insecticide-treated nets (ITNs, including long-lasting insecticidal nets and ...
Protocols for meta-analysis of intervention safety seldom specified methods to deal with rare events
(
Elsevier
, 2020 , Article Review)
ObjectivesMeta-analyses of rare events often generate unstable results, and selective reporting of the results may mislead the health care decision. Developing a synthesis plan for rare events in protocol may help to ...
Information, Thermodynamics and Life: A Narrative Review
(
MDPI
, 2021 , Article Review)
Information is probably one of the most difficult physical quantities to comprehend. This applies not only to the very definition of information, but also to the physical entity of information, meaning how can it be ...
Personalized telehealth in the future: A global research agenda
(
JMIR Publications Inc.
, 2016 , Article Review)
As telehealth plays an even greater role in global health care delivery, it will be increasingly important to develop a strong evidence base of successful, innovative telehealth solutions that can lead to scalable and ...
SARS-CoV-2 Infection and Lung Cancer: Potential Therapeutic Modalities.
(
MDPI
, 2020 , Article Review)
Human coronaviruses, especially SARS-CoV-2, are emerging pandemic infectious diseases with high morbidity and mortality in certain group of patients. In general, SARS-CoV-2 causes symptoms ranging from the common cold to ...
Current status of tissue engineering in the management of severe hypospadias
(
Frontiers Media S.A.
, 2018 , Article Review)
Hypospadias, characterized by misplacement of the urinary meatus in the lower side of the penis, is a frequent birth defect in male children. Because of the huge variation in the anatomic presentation of hypospadias, no ...
Targeting DNA Repair Pathways in Hematological Malignancies.
(
MDPI
, 2020 , Article Review)
DNA repair plays an essential role in protecting cells that are repeatedly exposed to endogenous or exogenous insults that can induce varying degrees of DNA damage. Any defect in DNA repair mechanisms results in multiple ...