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Impact of GGCX, STX1B and FPGS Polymorphisms on Warfarin Dose Requirements in European-Americans and Egyptians
(
Blackwell Publishing Ltd
, 2016 , Article)
Genotype-based algorithms that include VKORC1 and CYP2C9 genotypes are less predictive of warfarin dose variability in Africans as opposed to Europeans. Polymorphisms in GGCX, FPGS, or STX1B are associated with warfarin ...
Liposome Delivery Systems for Inhalation: A Critical Review Highlighting Formulation Issues and Anticancer Applications
(
S. Karger AG
, 2016 , Conference Paper)
This is a critical review on research conducted in the field of pulmonary delivery of liposomes. Issues relating to the mechanism of nebulisation and liposome composition were appraised and correlated with literature reports ...
The Therapeutic Effects of Camel Milk: A Systematic Review of Animal and Human Trials
(
SAGE Publications Ltd
, 2016 , Article Review)
The clinical effectiveness and value of camel milk as a therapeutic agent is currently unclear. MEDLINE (1946 to March 2016), EMBASE (1974 to March 2016), and Google Scholar were searched using the following terms: milk, ...
Targeting dopaminergic system for treating nicotine dependence
(
Bentham Science Publishers B.V.
, 2016 , Article)
Background: Smoking is the world's leading cause of preventable death among populations. Cigarette smoking increases the risk of numerous health problems, including heart diseases, stroke, atherosclerosis and many types ...
Role of pharmacist in cardiovascular disease-related health promotion and in hypertension and dyslipidemia management: A cross-sectional study in the State of Qatar
(
Blackwell Publishing Ltd
, 2016 , Article)
Rationale, aims and objectives In Qatar, cardiovascular diseases (CVD) have recently become the leading cause of morbidity and mortality. Prevention, detection and management of CVD risk factors reduce CVD chance. The study ...
Open-label study of absorption and clearance of 1% voriconazole eye drops
(
American Society for Microbiology
, 2016 , Article)
Twenty participants undergoing elective cataract surgery received 1% voriconazole eye drops (1 drop per eye) either 20, 40, 60, or 80 min before surgery. Median voriconazole concentrations of 1.9 to 3.2 mg/liter in aqueous ...
Evaluation of pharmacist-based compared to doctor-based anticoagulation management in Qatar
(
Blackwell Publishing Ltd
, 2016 , Article)
Rationale, aims and objectives For over 60 years, warfarin has been the mainstay anticoagulant used in the outpatient setting for the prevention and treatment of a wide variety of thromboembolic clinical conditions. ...
A Critical Review of the Current Evidence for Measuring Drug Concentrations of First-Line Agents Used to Treat Tuberculosis in Children
(
Springer International Publishing
, 2016 , Article Review)
Tuberculosis is a leading cause of infectious disease-related morbidity and mortality worldwide. Additionally, treatment is complex with most patients requiring combination therapy of first-line agents for multiple months. ...
Impact of a pharmacist-delivered discharge and follow-up intervention for patients with acute coronary syndromes in Qatar: A study protocol for a randomised controlled trial
(
BMJ Publishing Group
, 2016 , Article)
Introduction: Acute coronary syndrome (ACS) is one of the leading causes of morbidity and mortality worldwide. Secondary cardiovascular risk reduction therapy (consisting of an aspirin, a ?-blocker, an ACE inhibitor or an ...
Design and synthesis of novel chalcones as potent selective monoamine oxidase-B inhibitors
(
Elsevier Masson SAS
, 2016 , Article)
A novel series of substituted chalcones were designed and synthesized to be evaluated as selective human MAO-B inhibitors. A combination of either methylsulfonyl or trifluoromethyl substituents on the aromatic ketone moiety ...