Algae-derived bioactive compounds with anti-lung cancer potential
المؤلف | Saadaoui, Imen |
المؤلف | Rasheed, Rihab |
المؤلف | Abdulrahman, Nabeel |
المؤلف | Bounnit, Touria |
المؤلف | Cherif, Maroua |
المؤلف | Al Jabri, Hareb |
المؤلف | Mraiche, Fatima |
تاريخ الإتاحة | 2023-02-20T04:49:43Z |
تاريخ النشر | 2020-01-01 |
اسم المنشور | Marine Drugs |
المعرّف | http://dx.doi.org/10.3390/md18040197 |
الاقتباس | Saadaoui, I.; Rasheed, R.; Abdulrahman, N.; Bounnit, T.; Cherif, M.; Al Jabri, H.; Mraiche, F. Algae-Derived Bioactive Compounds with Anti-Lung Cancer Potential. Mar. Drugs 2020, 18, 197. https://doi.org/10.3390/md18040197 |
الملخص | Lung cancer is one of the major causes of death worldwide. Natural molecules with anti-lung cancer potential are of a great interest and considered as very promising alternative to substitute or enhance the efficiency of the conventional drugs. Recently, algae as source of high value-added compounds are considered as very promising source of these bioactive molecules. These are secondary metabolites that consist mainly of derivatives of peptides, carbohydrates, and lipids with various structures. Accordingly, various mechanisms by which different algae molecules demonstrate attenuation of tumor angiogenesis were stated and discussed. The mode of action of the algae bioactives is closely related to their nature and chemical structure. Furthermore, this literature review considers the synergistic effect between microalgae bioactives and conventional drugs and discuss the economic feasibility of producing microalgae bioactives at large scale to conclude with some future perspectives related to algae-based drug discovery. |
راعي المشروع | This research was funded by Qatar National Research Fund, grant number “NPRP8-1087-1-207”. |
اللغة | en |
الناشر | MDPI |
الموضوع | Bioactives Drug discovery Lung cancer Marine algae Mode of action Molecular target |
النوع | Article Review |
رقم العدد | 4 |
رقم المجلد | 18 |
ESSN | 1660-3397 |
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