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المؤلفSaadaoui, Imen
المؤلفRasheed, Rihab
المؤلفAbdulrahman, Nabeel
المؤلفBounnit, Touria
المؤلفCherif, Maroua
المؤلفAl Jabri, Hareb
المؤلفMraiche, Fatima
تاريخ الإتاحة2023-02-20T04:49:43Z
تاريخ النشر2020-01-01
اسم المنشورMarine Drugs
المعرّفhttp://dx.doi.org/10.3390/md18040197
الاقتباسSaadaoui, I.; Rasheed, R.; Abdulrahman, N.; Bounnit, T.; Cherif, M.; Al Jabri, H.; Mraiche, F. Algae-Derived Bioactive Compounds with Anti-Lung Cancer Potential. Mar. Drugs 2020, 18, 197. https://doi.org/10.3390/md18040197
معرّف المصادر الموحدhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85083276616&origin=inward
معرّف المصادر الموحدhttp://hdl.handle.net/10576/40141
الملخصLung cancer is one of the major causes of death worldwide. Natural molecules with anti-lung cancer potential are of a great interest and considered as very promising alternative to substitute or enhance the efficiency of the conventional drugs. Recently, algae as source of high value-added compounds are considered as very promising source of these bioactive molecules. These are secondary metabolites that consist mainly of derivatives of peptides, carbohydrates, and lipids with various structures. Accordingly, various mechanisms by which different algae molecules demonstrate attenuation of tumor angiogenesis were stated and discussed. The mode of action of the algae bioactives is closely related to their nature and chemical structure. Furthermore, this literature review considers the synergistic effect between microalgae bioactives and conventional drugs and discuss the economic feasibility of producing microalgae bioactives at large scale to conclude with some future perspectives related to algae-based drug discovery.
راعي المشروعThis research was funded by Qatar National Research Fund, grant number “NPRP8-1087-1-207”.
اللغةen
الناشرMDPI
الموضوعBioactives
Drug discovery
Lung cancer
Marine algae
Mode of action
Molecular target
العنوانAlgae-derived bioactive compounds with anti-lung cancer potential
النوعArticle Review
رقم العدد4
رقم المجلد18
ESSN1660-3397
dc.accessType Open Access


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