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AuthorSaadaoui, Imen
AuthorRasheed, Rihab
AuthorAbdulrahman, Nabeel
AuthorBounnit, Touria
AuthorCherif, Maroua
AuthorAl Jabri, Hareb
AuthorMraiche, Fatima
Available date2023-02-20T04:49:43Z
Publication Date2020-01-01
Publication NameMarine Drugs
Identifierhttp://dx.doi.org/10.3390/md18040197
CitationSaadaoui, I.; Rasheed, R.; Abdulrahman, N.; Bounnit, T.; Cherif, M.; Al Jabri, H.; Mraiche, F. Algae-Derived Bioactive Compounds with Anti-Lung Cancer Potential. Mar. Drugs 2020, 18, 197. https://doi.org/10.3390/md18040197
URIhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85083276616&origin=inward
URIhttp://hdl.handle.net/10576/40141
AbstractLung cancer is one of the major causes of death worldwide. Natural molecules with anti-lung cancer potential are of a great interest and considered as very promising alternative to substitute or enhance the efficiency of the conventional drugs. Recently, algae as source of high value-added compounds are considered as very promising source of these bioactive molecules. These are secondary metabolites that consist mainly of derivatives of peptides, carbohydrates, and lipids with various structures. Accordingly, various mechanisms by which different algae molecules demonstrate attenuation of tumor angiogenesis were stated and discussed. The mode of action of the algae bioactives is closely related to their nature and chemical structure. Furthermore, this literature review considers the synergistic effect between microalgae bioactives and conventional drugs and discuss the economic feasibility of producing microalgae bioactives at large scale to conclude with some future perspectives related to algae-based drug discovery.
SponsorThis research was funded by Qatar National Research Fund, grant number “NPRP8-1087-1-207”.
Languageen
PublisherMDPI
SubjectBioactives
Drug discovery
Lung cancer
Marine algae
Mode of action
Molecular target
TitleAlgae-derived bioactive compounds with anti-lung cancer potential
TypeArticle Review
Issue Number4
Volume Number18
ESSN1660-3397
dc.accessType Open Access


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