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Current status of tissue engineering in the management of severe hypospadias
(
Frontiers Media S.A.
, 2018 , Article Review)
Hypospadias, characterized by misplacement of the urinary meatus in the lower side of the penis, is a frequent birth defect in male children. Because of the huge variation in the anatomic presentation of hypospadias, no ...
The Spectrum of Mutations of Homocystinuria in the MENA Region
(
MDPI
, 2020 , Article Review)
Homocystinuria is an inborn error of metabolism due to the deficiency in cystathionine beta-synthase (CBS) enzyme activity. It leads to the elevation of both homocysteine and methionine levels in the blood and urine. ...
Cellular and molecular targets of menthol actions
(
Frontiers Media S.A.
, 2017 , Article Review)
Menthol belongs to monoterpene class of a structurally diverse group of phytochemicals found in plant-derived essential oils. Menthol is widely used in pharmaceuticals, confectionary, oral hygiene products, pesticides, ...
Understanding the Burden of Atopic Dermatitis in Africa and the Middle East
(
Springer Healthcare
, 2019 , Article Review)
Atopic dermatitis (AD) is a common inflammatory skin disease characterized by intensely pruritic lesions. The prevalence of atopic dermatitis is increasing in developing regions, including Africa and the Middle East. ...
SARS-CoV-2 Infection and Lung Cancer: Potential Therapeutic Modalities.
(
MDPI
, 2020 , Article Review)
Human coronaviruses, especially SARS-CoV-2, are emerging pandemic infectious diseases with high morbidity and mortality in certain group of patients. In general, SARS-CoV-2 causes symptoms ranging from the common cold to ...
The Role of Epstein-Barr Virus in Cervical Cancer: A Brief Update.
(
Frontiers Media
, 2018 , Article Review)
Epstein-Barr virus (EBV) belongs to the group of gamma-herpes viruses and was the first recognized human oncovirus. EBV is responsible for infectious mononucleosis and multiple lymphoid and epithelial malignancies including ...
DNA Damage/Repair Management in Cancers
(
MDPI
, 2020 , Article Review)
DNA damage is well recognized as a critical factor in cancer development and progression. DNA lesions create an abnormal nucleotide or nucleotide fragment, causing a break in one or both chains of the DNA strand. When DNA ...
Comparative effectiveness of malaria prevention measures: a systematic review and network meta-analysis.
(
BMC
, 2018 , Article Review)
Malaria causes significant morbidity and mortality worldwide. There are several preventive measures that are currently employed, including insecticide-treated nets (ITNs, including long-lasting insecticidal nets and ...
IP3 receptors and their intimate liaisons
(
Elsevier
, 2020 , Article Review)
Inositol 1,4,5-trisphosphate receptors (IP3Rs) are intracellular Ca2+ channels. They allow cell-surface receptors that stimulate IP3 formation to evoke rapid Ca2+ release from the endoplasmic reticulum (ER). IP3Rs initiate ...
Giant parathyroid adenoma: A case report and review of the literature
(
BioMed Central Ltd.
, 2019 , Article Review)
Background: Giant parathyroid adenoma is a rare type of parathyroid adenoma defined as weighing > 3.5 g. They present as primary hyperparathyroidism but with more elevated laboratory findings and more severe clinical ...