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AuthorShah, Naheed Sidiq
AuthorThotathil, Vandana
AuthorZaidi, Shabi Abbas
AuthorSheikh, Hanan
AuthorMohamed, Maimoona
AuthorQureshi, Ahmadyar
AuthorSadasivuni, Kishor Kumar
Available date2023-05-17T08:32:07Z
Publication Date2022-12-01
Publication NameBiosensors
Identifierhttp://dx.doi.org/10.3390/bios12121107
CitationShah, N. S., Thotathil, V., Zaidi, S. A., Sheikh, H., Mohamed, M., Qureshi, A., & Sadasivuni, K. K. (2022). Picomolar or beyond Limit of Detection Using Molecularly Imprinted Polymer-Based Electrochemical Sensors: A Review. Biosensors, 12(12), 1107.
URIhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85144500886&origin=inward
URIhttp://hdl.handle.net/10576/42843
AbstractOver the last decades, molecularly imprinted polymers (MIPs) have emerged as selective synthetic receptors that have a selective binding site for specific analytes/target molecules. MIPs are synthetic analogues to the natural biological antigen–antibody system. Owing to the advantages they exhibit, such as high stability, simple synthetic procedure, and cost-effectiveness, MIPs have been widely used as receptors/sensors for the detection and monitoring of a variety of analytes. Moreover, integrating electrochemical sensors with MIPs offers a promising approach and demonstrates greater potential over traditional MIPs. In this review, we have compiled the methods and techniques for the production of MIP-based electrochemical sensors along with the applications of reported MIP sensors for a variety of analytes. A comprehensive in-depth analysis of recent trends reported on picomolar (pM/10−12 M)) and beyond picomolar concentration LOD (≥pM) achieved using MIPs sensors is reported. Finally, we discuss the challenges faced and put forward future perspectives along with our conclusion.
SponsorThis work was supported by the UREP grant # UREP28-063-1-008 from the Qatar National Research Fund (QNRF).
Languageen
PublisherMultidisciplinary Digital Publishing Institute (MDPI)
Subjectelectrochemical sensors
limit of detection
molecular imprinted polymer
ultrasensitive
TitlePicomolar or beyond Limit of Detection Using Molecularly Imprinted Polymer-Based Electrochemical Sensors: A Review
TypeArticle
Issue Number12
Volume Number12
ESSN2079-6374
dc.accessType Open Access


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