تصفح Biomedical Research Center Research حسب العنوان
السجلات المعروضة 141 -- 160 من 727
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Covid-19: Challenges & Perspectives
( College of Medicine - Qatar University , 2020 , Video)A Virtual Conference to shed light on the QU's prominent trends and research efforts addressing Corona virus. -
Crosstalk between HER2 and PD-1/PD-L1 in Breast Cancer: From Clinical Applications to Mathematical Models.
( Springer , 2020 , Article)Breast cancer is one of the major causes of mortality in women worldwide. The most aggressive breast cancer subtypes are human epidermal growth factor receptor-positive (HER2) and triple-negative breast cancers. Therapies ... -
Crosstalk between Microglia and Neurons in Neurotrauma: An Overview of the Underlying Mechanisms.
( Bentham Science Publishers , 2022 , Article Review)Microglia are the resident immune cells of the brain and play a crucial role in housekeeping and maintaining homeostasis of the brain microenvironment. Upon injury or disease, microglial cells become activated, at least ... -
Crosstalk between Sodium–Glucose Cotransporter Inhibitors and Sodium–Hydrogen Exchanger 1 and 3 in Cardiometabolic Diseases
( MDPI , 2021 , Article)Abnormality in glucose homeostasis due to hyperglycemia or insulin resistance is the hallmark of type 2 diabetes mellitus (T2DM). These metabolic abnormalities in T2DM lead to cellular dysfunction and the development of ... -
Cryptosporidium spp., prevalence, molecular characterisation and socio-demographic risk factors among immigrants in Qatar.
( Public Library of Science , 2019 , Article)The World Health Organization WHO has estimated that in developed countries, up to 30% of the population may suffer from foodborne diseases each year, and that in developing countries up to 2 million deaths per annum can ... -
CTGF Loaded Electrospun Dual Porous Core-Shell Membrane For Diabetic Wound Healing
( Dove Medical Press Ltd. , 2019 , Article)Purpose: Impairment of wound healing is a major issue in type-2 diabetes that often causes chronic infections, eventually leading to limb and/or organ amputation. Connective tissue growth factor (CTGF) is a signaling ... -
Curcumin a Colorimetric and Fluorimetric Cyanide Probe in Aqueous System and Living Cells
( Royal Society of Chemistry , 2019 , Article)Curcumin, 1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-hepta-diene-3,5-dione, is a natural product obtained from the rhizome of Curcuma longa. Curcumin has been demonstrated to be a strong antioxidant with anticancer properties ... -
The Current Status of Cytomegalovirus (CMV) Prevalence in the MENA region: a systematic review
( MDPI , 2019 , Article)Human cytomegalovirus (CMV) is a highly prevalent herpesvirus worldwide. According to the Centers for Disease Control and Prevention (CDC) and the World Health Organization (WHO), CMV infects people of all ages, and by ... -
Cysteamine revisited: repair of arginine to cysteine mutations.
( Springer Verlag , 2017 , Article)Cysteamine is a small aminothiol endogenously derived from coenzyme A degradation. For some decades, synthetic cysteamine has been employed for the treatment of cystinosis, and new uses of the drug continue to emerge. In ... -
Cytoprotective, antioxidant, and anti-migratory activity of Pistacia lentiscus L. supercritical carbon dioxide extract on primary human endothelial cells
( Taylor & Francis , 2022 , Article)Green chemistry is a useful tool for producing valuable chemicals from biomass. However, extracted compounds need to be tested for safety and efficacy before their use in humans. Here we investigate the chemical composition ... -
Cytotoxicity and physicochemical characterization of iron–manganese-doped sulfated zirconia nanoparticles
( Dove Press , 2015 , Article)Iron–manganese-doped sulfated zirconia nanoparticles with both Lewis and Brønsted acidic sites were prepared by a hydrothermal impregnation method followed by calcination at 650°C for 5 hours, and their cytotoxicity ... -
A decade of intestinal protozoan epidemiology among settled immigrants in Qatar
( PubMed Central , 2016 , Article)Background: The World Health Organization estimates that about 3.5 billion people worldwide are affected by intestinal parasitic infections. Reports have already emphasized the role of immigrants in outbreaks of ... -
Deep Learning Technique for Congenital Heart Disease Detection Using Stacking-Based CNN-LSTM Models from Fetal Echocardiogram: A Pilot Study
( IEEE , 2023 , Article)Congenital heart defects (CHDs) are a leading cause of death in infants under 1 year of age. Prenatal intervention can reduce the risk of postnatal serious CHD patients, but current diagnosis is based on qualitative criteria, ... -
Demographic and Clinical Characteristics of Early Travel-Associated COVID-19 Cases
( Frontiers Media , 2020 , Article)© Copyright © 2020 Marei, Emara, Elsaied, Nasrallah, Chivese, Al-Romaihi, Althani, Al Thani, Farag and Yassine. Background: SARS-CoV-2 continues to claim hundreds of thousands of people's lives. It mostly affects the elderly ... -
Demographics and Epidemiology of Hepatitis B in the State of Qatar: A Five-Year Surveillance-Based Incidence Study
( MDPI , 2019 , Article)Background: Expatriates represent >80% of Qatar’s population, mostly arriving from countries in Africa and Asia that are endemic with many diseases. This increases the risk for introducing new pathogens into the country ... -
Denaturing Gradient Gel Electrophoresis-Polymerase Chain Reaction Comparison of Chitosan Effects on Anaerobic Cultures of Broiler Cecal Bacteria and Salmonella Typhimurium.
( Mary Ann Liebert , 2018 , Article)Enteropathogen colonization and product contamination are major poultry industry problems. The emergence of antibiotic resistance, and associated risks to human health, is limiting the use of antibiotics as first-line ... -
Design and Microinjection of Morpholino Antisense Oligonucleotides and mRNA into Zebrafish Embryos to Elucidate Specific Gene Function in Heart Development
( MyJove Corporation , 2022 , Article)The morpholino oligomer-based knockdown system has been used to identify the function of various gene products through loss or reduced expression. Morpholinos (MOs) have the advantage in biological stability over DNA oligos ... -
Design of hybrid clay/ polypyrrole decorated with silver and zinc oxide nanoparticles for anticorrosive and antibacterial applications
( Elsevier , 2020 , Article)In this work, a novel and cost-effective bentonite intercalated with polypyrrole Zinc oxide-silver nanocomposite (B-PPy/ZnO) hybrid material was prepared via in situ photopolymerization of pyrrole in the presence of silanized ... -
Design of Nanoparticulate Group 2 Influenza Virus Hemagglutinin Stem Antigens That Activate Unmutated Ancestor B Cell Receptors of Broadly Neutralizing Antibody Lineages.
( American Society for Microbiology , 2019 , Article)Influenza vaccines targeting the highly conserved stem of the hemagglutinin (HA) surface glycoprotein have the potential to protect against pandemic and drifted seasonal influenza viruses not covered by current vaccines. ... -
Design, synthesis, and validation of novel nitrogen-based chalcone analogs against triple negative breast cancer
( Elsevier Masson s.r.l. , 2020 , Article)Great strides have been made in triple negative breast cancer (TNBC) treatment, which represents 20% of total predicted annual US breast cancer (BC) cases. Despite the development of several therapeutics, TNBC patients ...