Browsing Biomedical Sciences by Author "Al-Dewik, Nader"
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Assessment of the Neutralizing Antibody Response of BNT162b2 and mRNA-1273 SARS-CoV-2 Vaccines in Naïve and Previously Infected Individuals: A Comparative Study
Shurrab, Farah M.; Al-Sadeq, Duaa W.; Abou-Saleh, Haissam; Al-Dewik, Nader; Elsharafi, Amira E.; Hamaydeh, Fatima M.; Abo Halawa, Bushra Y.; Jamaleddin, Tala M.; Abdul Hameed, Huda M.; Nizamuddin, Parveen B.; Amanullah, Fathima Humaira; Daas, Hanin I.; Abu-Raddad, Laith J.; Nasrallah, Gheyath K.... more authors ... less authors ( MDPI , 2022 , Report)The currently authorized mRNA COVID-19 vaccines, Pfizer-BNT162b2 and Moderna-mRNA-1273, offer great promise for reducing the spread of the COVID-19 by generating protective immunity against SARS-CoV-2. Recently, it was ... -
Biochemical and structural impact of two novel missense mutations in cystathionine β-synthase gene associated with homocystinuria
Al-Sadeq, Duaa W.; Conter, Carolina; Thanassoulas, Angelos; Al-Dewik, Nader; Safieh-Garabedian, Bared; Martínez-Cruz, Luis Alfonso; Nasrallah, Gheyath K.; Astegno, Alessandra; Nomikos, Michail... more authors ... less authors ( Portland Press Ltd , 2024 , Article)Homocystinuria is a rare disease caused by mutations in the CBS gene that results in a deficiency of cystathionine β-synthase (CBS). CBS is an essential pyridoxal 50-phosphate (PLP)-dependent enzyme in the transsulfuration ... -
Diagnostic Efficiency of Three Fully Automated Serology Assays and Their Correlation with a Novel Surrogate Virus Neutralization Test in Symptomatic and Asymptomatic SARS-COV-2 Individuals
Younes, Salma; Al-Jighefee, Hadeel; Shurrab, Farah; Al-Sadeq, Duaa W.; Younes, Nadin; Dargham, Soha R.; Al-Dewik, Nader; Qotba, Hamda; Syed, Mohamed; Alnuaimi, Ahmed; Yassine, Hadi M.; Tang, Patrick; Abu-Raddad, Laith J.; Nasrallah, Gheyath K.... more authors ... less authors ( MDPI , 2020 , Article)Abstract: To support the deployment of serology assays for population screening during the COVID-19 pandemic, we compared the performance of three fully automated SARS-CoV-2 IgG assays: Mindray CL-900i® (target: spike [S] ... -
Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals over 10 months
Salma, Younes; Nicolai, Eleonora; Al-Sadeq, Duaa W.; Younes, Nadin; Al-Dewik, Nader; Abou-Saleh, Haissam; Abo-Halawa, Bushra Y.; Eid, Ali Hussein; Pieri, Massimo; Liu, Na; Daas, Hanin I.; Yassine, Hadi M.; Nizamuddin, Parveen B.; Abu-Raddad, Laith J.; Nasrallah, Gheyath K.... more authors ... less authors ( Elsevier , 2023 , Article)BackgroundEvidence on the effectiveness of vaccination-induced immunity compared to SARS-CoV-2 natural immunity is warranted to inform vaccination recommendations. AimIn this study, we aimed to conduct a comparative ... -
Incidence, Risk Factors, and Outcomes of Preterm and Early Term Births: A Population-Based Register Study
Younes, Salma; Samara, Muthanna; Al-Jurf, Rana; Nasrallah, Gheyath; Al-Obaidly, Sawsan; Salama, Husam; Olukade, Tawa; Hammuda, Sara; Ismail, Mohamed; Abdoh, Ghassan; Abdulrouf, Palli Valapila; Farrell, Thomas; AlQubaisi, Mai; Al Rifai, Hilal; Al-Dewik, Nader... more authors ... less authors ( MDPI , 2021 , Article)Preterm birth (PTB) and early term birth (ETB) are associated with high risks of perinatal mortality and morbidity. While extreme to very PTBs have been extensively studied, studies on infants born at later stages of ... -
Prevalence and Phylogenetic Analysis of Parvovirus (B19V) among Blood Donors with Different Nationalities Residing in Qatar
Abdelrahman, Doua; Al-Sadeq, Duaa W.; Smatti, Maria K.; Taleb, Sara A.; AbuOdeh, Raed O.; Al-Absi, Enas S.; Al-Thani, Asmaa A.; Coyle, Peter. V.; Al-Dewik, Nader; Al Qahtani, Ahmed A.; Yassine, Hadi M.; Nasrallah, Gheyath K.... more authors ... less authors ( MDPI , 2021 , Article)Human parvovirus (B19V) is the causative agent of erythema infectiosum in children and is linked to a wide range of clinical manifestations. Studies related to B19V prevalence in the Middle East and North Africa (MENA) ...